Physiology 101 - Introduction to Human Physiology » Fall 2020 » Lecture Exam 1

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Question #1
"Osmosis" refers to the movement of what substance across semipermeable membranes?
A.   Charged particles
B.   Glucose
C.   Lipid molecules
D.   Water
E.   Solutes
Question #2
Carbon-12 and carbon-14 are isotopes. How are they different from each other?
A.   They can form different numbers of chemical bonds.
B.   They have different numbers of electrons.
C.   They have different number of energy shells
D.   They have different numbers of neutrons.
E.   They have different numbers of protons.
Question #3
Water molecules can form covalent bonds with other water molecules.
A.   FALSE
B.   TRUE
Question #4
Which of the following is a type of molecular interaction that determines the tertiary structure of a protein? (Choose all that could apply),,
A.   Covalent bonds between purine and pyrimidine bases
B.   Van der Waals forces
C.   Bonds between two cysteine amino acids
D.   Ionic bonds
E.   Hydrogen bonds
Question #5
How many electrons are found in the outer shell of an oxygen atom?
A.   8
B.   6
C.   1
D.   2
E.   4
Question #6
Which would be true if substance X was moving into a cell by primary active transport?
A.   A cell is placed into a 1 millimolar solution of substance X and over time you witness the size of the cell shrink.
B.   A cell is placed into a 1 millimolar solution of substance X and over time you witness the concentration of X inside the cell increase to 5 millimolar.
C.   A cell is placed into a 1 millimolar solution of substance X and over time you witness the concentration of X inside the cell decrease to 0.5 millimolar.
D.   A cell is placed into a 1 millimolar solution of substance X and over time you witness the size of the cell swell.
E.   A cell is placed into a 1 millimolar solution of substance X and over time you witness the concentration of X inside the cell increase to 1 millimolar.
Question #7
The fate of all endocytotic vesicles is digestion of their contents by lysosomal enzymes.
A.   TRUE
B.   FALSE
Question #8
Lysosomes are organelles specialized for breaking down intracellular debris or malfunctioning parts of cells.
A.   FALSE
B.   TRUE
Question #9
What will happen if a normal cell is placed in a hypotonic solution?
A.   It will swell in size.
B.   It will shrink in size.
C.   It will stay the same size.
D.   The result can't be predicted
Question #10
Which form of endocytosis is nonspecific, in that it occurs by the formation of an invagination of the plasma membrane, which then fills with interstitial fluid of the immediate area?
A.   Hyperosmotic vesicular entrapment
B.   Hydrosmosis
C.   Active transport
D.   Pinocytosis
E.   Phagocytosis
Question #11
Chromosomes are composed mainly of DNA.
A.   FALSE
B.   TRUE
Question #12
Molecules that have properties of both polar and nonpolar molecules are called
A.   amphipathic.
B.   unipolar.
C.   hydrophobic.
D.   bipolar.
E.   hydrophilic.
Question #13
When magnesium loses electrons to become an ion, what does it become?
A.   A covalent molecule
B.   A free radical
C.   An anion
D.   A new element
E.   A cation
Question #14
In DNA, thymine binds with adenine and cytosine binds with uracil.
A.   FALSE
B.   TRUE
Question #15
A pediatric patient presents with recurring bacterial infections. This could be due to a defect in phagocytosis.
A.   FALSE
B.   TRUE
Question #16
Substance X is a mostly polar molecule and Substance Y is a mostly non-polar molecule of a similar size. You create an artificial cell surrounded by a phospholipid bilayer that is made only of phospholipids. Which will diffuse from the extracellular fluid to the intracellular fluid faster if they are in unequal concentrations outside and inside the cell?
A.   Substance Y will diffuse faster.
B.   Substance X and Substance Y will diffuse at the same rate, as they are of equal size and concentration.
C.   Substance X will diffuse faster.
Question #17
The promoter sequence of nucleotides in a gene is present on both strands of the DNA molecule, allowing transcription of both strands.
A.   FALSE
B.   TRUE
Question #18
A single genetic mutation will change a protein at what level of structure? (Choose all that could apply),,
A.   Primary
B.   Quaternary
C.   Secondary
D.   Tertiary
Question #19
Which organelles would you expect to be especially numerous in cells such as muscle cells that have a tremendous demand for energy in the form of ATP?
A.   Endosomes
B.   Lysosomes
C.   Ribosomes
D.   Peroxisomes
E.   Mitochondria
Question #20
Which is NOT a function of the Golgi apparatus?
A.   Addition of carbohydrate groups to proteins
B.   Sorting of proteins destined for various locations in the cell
C.   Modifying proteins destined for secretion
D.   Transcribing a signal sequence onto proteins destined for secretion
E.   Packaging enzymes destined for lysosomes
Question #21
Which of the following is not true of the cytoskeleton?
A.   It refers to the cellular components of bone.
B.   It helps to determine a cell's shape.
C.   It includes actin filaments.
D.   It is important for cellular movement.
E.   It refers to a network of cytoplasmic filaments.
Question #22
Neurons have a very prominent nucleolus, which indicates that they are actively performing what function?
A.   Making ATP
B.   Synthesizing lipids
C.   Breaking down carbohydrates
D.   Dividing by mitosis
E.   Manufacturing ribosomes
Question #23
If a protein’s conformation changes it is likely that its function will change as well.
A.   FALSE
B.   TRUE
Question #24
Ion channels in cell membranes
A.   are not affected by differences in electrical potential across the membrane.
B.   are nonspecific.
C.   may open in response to binding a ligand.
D.   only allow ions to move from the extracellular fluid into the cell.
E.   only allow ions to move from the intracellular fluid out of the cell.
Question #25
Which of the following is not true of a polar chemical bond?
A.   It is covalent.
B.   It is ionized.
C.   It has opposite electrical charge at each end.
D.   It has no net electrical charge.
Question #26
The number of covalent bonds that can be formed by a given atom depends upon the number of electrons present in the outermost orbit.
A.   FALSE
B.   TRUE
Question #27
Which is true about mediated transport of substances across cell membranes?
A.   It involves a specific membrane protein that functions as a carrier molecule.
B.   There is no limit to how fast it can occur as the concentration gradient becomes larger.
C.   It always involves the movement of substances against a concentration gradient.
D.   It is the main mechanism fortransportinghydrophobic molecules across membranes.
E.   It is always directly coupled to the splitting of ATP molecules.
Question #28
Which is a major function of the plasma membrane?
A.   Regulating the passage of molecules into and out of the cell
B.   Storing calcium ions
C.   Providing genetic information
D.   Storing organic chemicals for metabolism
E.   Generating ATP
Question #29
Which of the following correctly describes the structure of a gene?
A.   It starts with a promoter, then is followed by a 5' UTR, a coding sequence and then a 3'UTR
B.   It starts with a UTR sequence, then is followed by a promoter and then the coding sequence
C.   It starts with a promoter, then is followed by a 5' UTR, a 3'UTR and then the coding sequence
D.   It starts with a promoter, then is followed by a 3' UTR, a coding sequence and then a 5'UTR
Question #30
Transcription factors activate or repress the transcription of specific genes by binding to regions of DNA that interact with the promoter region of a gene.
A.   FALSE
B.   TRUE
Question #31
Which of the following contain phosphate groups?,,
A.   Cholesterol
B.   Nucleotides
C.   Amino acids
D.   Monosaccharides
E.   Phospholipids
Question #32
Once protein synthesis is completed, the protein that was synthesized may undergo further changes prior to its secretion or use within the cell.
A.   FALSE
B.   TRUE
Question #33
Dehydration reactions among glucose monomers will produce polysaccharides such as glycogen and cellulose
A.   FALSE
B.   TRUE
Question #34
Intracellular fluid is defined as the fluid in the cytosol and organelles.
A.   TRUE
B.   FALSE
Question #35
Macrophages are cells that engulf and digest bacteria and cell debris. To perform the digestive function, macrophages tend to have more __________ than other cells.
A.   mitochondria
B.   ribosomes
C.   lysosomes
D.   peroxisomes
E.   endosomes
Question #36
Hydrolysis of glycogen will have what effect on blood glucose level?
A.   No effect on blood glucose level
B.   Decrease blood glucose level
C.   Increase blood glucose level
Question #37
The reactions of the Krebs cycle
A.   take place in the cytosol of human cells.
B.   generate ATP and the electron carrier NADH
C.   generate ATP and electron carriers NADH and FADH2
D.   produce pyruvate and lactate as end products.
E.   take place only when no oxygen is present.
Question #38
Which of these is an example of a hypertonic solution?
A.   100 mM NaCl
B.   300 mM glucose
C.   100 mM MgCl 2
D.   200 mM NaCl
E.   400 mM urea
Question #39
One function of integral membrane proteins in the plasma membrane of cells is to form channels to allow passage of nonpolar solutes into the cell.
A.   FALSE
B.   TRUE
Question #40
Which of these processes can occur without the direct use of ATP? Choose all that could apply.,,
A.   None of these can occur without the direct use of ATP
B.   Facilitated diffusion
C.   Secondary active transport
D.   Simple diffusion
E.   Primary active transport
Question #41
Your colleague has discovered a new species and you are viewing one of the cells under the electron microscope. You see a large, oval-shaped structure in the center of the cell, surrounded by a membrane. After this observation, you hypothesize that the cells of this species are prokaryotic cells.
A.   FALSE
B.   TRUE
Question #42
Which of the following metabolic pathways can proceed in the absence of oxygen?
A.   The breakdown of fatty acids to CO 2 and H 2O
B.   Krebs cycle
C.   None of the choices are correct.
D.   Glycolysis
E.   Oxidative phosphorylation
Question #43
Regarding the tonicity and osmolarity of solutions, which of the following statements is not true?
A.   The term "osmolarity" refers to the osmotic properties of a solution, regardless of its tonicity.
B.   Hypoosmotic solutions are always hypotonic.
C.   The term "tonicity" refers to the effect that a solution has on the degree of stretch or shrinking of the cell membrane.
D.   Isotonic solutions are always isoosmotic.
E.   Hypertonic solutions are always hyperosmotic.
Question #44
Which of the following statements regarding the structure and function of cell membranes is correct?
A.   Peripheral membrane proteins function as channels associated with transport of ions through the membrane.
B.   The phospholipid bilayer is arranged so that the hydrophilic heads of the phospholipid molecule face the extra- and intracellular fluids.
C.   Cholesterol molecules function to transport ions from one side of the plasma membrane to the other.
D.   The plasma membrane is a layer of phospholipid molecules with their hyrophilic head groups in contact with the extracellular solution and the hydrophobic tail groups in contact with the intracellular solution.
E.   Some proteins integrated into the membrane serve as channels for the passage of nonpolar molecules through the membrane.
Question #45
The secondary structure of a polypeptide is formed by ionic bonds between amino groups and carboxyl groups
A.   FALSE
B.   TRUE
Question #46
The major lipids in cellular membranes are phospholipids.
A.   TRUE
B.   FALSE
Question #47
Glycoproteins are protein molecules with molecules of glycogen attached to the amino acid side chains.
A.   FALSE
B.   TRUE
Question #48
  
A.   FALSE
B.   TRUE
Question #49
Which of these are functions of the Golgi apparatus?
A.   Synthesizing lipids and intracellular storage of calcium ions
B.   Modifying proteins synthesized on ribosomes associated with granular endoplasmic reticulum and allowing the distribution of modified proteins throughout the cell in vesicles
C.   Digestion of engulfed bacteria and using oxygen to generate ATP
D.   Modifying proteins synthesized on free ribosomes and allowing the distribution of modified proteins throughout the cell in vesicles
E.   Modifying proteins synthesized on free ribosomes and storing calcium ions
Question #50
What are the products of glycolysis under anaerobic conditions?
A.   2 molecules of NADH and 2 molecules of water
B.   2 molecules of pyruvate, 2 molecules of water, and 2 NADH
C.   2 molecules of ATP, 2 molecules of water, and 2 molecules of lactate
D.   2 molecules of pyruvate, 2 molecules of lactate, and 2 ATP
E.   2 molecules of pyruvate and 36 molecules of ATP
Question #51
During oxidative phosphorylation, hydrogen atoms are passed serially from a coenzyme down a chain of molecules called cytochromes.
A.   TRUE
B.   FALSE
Question #52
CO 2 is a small, non-polar molecule. It will cross the cell membrane by
A.   diffusion through a channel.
B.   simple diffusion.
C.   diffusion using a pump.
D.   active transport.
Question #53
Peripheral membrane proteins are involved in regulating cell shape and motility.
A.   TRUE
B.   FALSE
Question #54
The Na/K ATPase pump is an enzyme that phosphorylates itself.
A.   FALSE
B.   TRUE

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