Physiology 001 - Introduction to Human Physiology » Winter 2021 » Lecture Exam 1 (A)
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Question #1
Physiology is the study of
A.
how two organisms interact.
B.
the spread of diseases.
C.
the structure of the body.
D.
two of the choices are correct.
E.
how organisms function.
Question #2
Differentiation is necessary before a cell can exchange material with its environment.
A.
FALSE
B.
TRUE
Question #3
Which of components of a general reflex arc are listed in the order information typically flows through them following a stimulus?
A.
Receptor, afferent pathway, integrating center, efferent pathway, effector
B.
Receptor, efferent pathway, integrating center, afferent pathway, effector
C.
Effector, afferent pathway, integrating center, efferent pathway, receptor
D.
Integrating center, receptor, afferent pathway, efferent pathway, effector
E.
Effector, efferent pathway, integrating center, afferent pathway, receptor
Question #4
When loss of a substance from the body exceeds gain, the body is said to be in positive balance for that substance.
A.
FALSE
B.
TRUE
Question #5
The respiratory system is primarily responsible for transporting blood to the body's tissues.
A.
TRUE
B.
FALSE
Question #6
What is the location of the internal pacemaker that sets biological rhythms?
A.
Photoreceptors of the eye
B.
Ventricles of the heart
C.
Endocrine gland in the gonads
D.
The adrenal glands
E.
Suprachiasmatic nucleus of the brain
Question #7
If the amount of sodium in the blood decreases, what would a negative feedback control mechanism be expected to do?
A.
Change the set point for sodium
B.
Leave the amount of sodium unchanged
C.
Decrease the amount of sodium in the blood
D.
Increase the amount of sodium in the blood
E.
Inhibit the ingestion of more sodium
Question #8
A protein may consist of more than one polypeptide chain.
A.
FALSE
B.
TRUE
Question #9
Which is a correct description of nucleic acids?
A.
They are polymers of subunits containing glucose, a phosphate group, and an amino acid.
B.
They are polymers of subunits containing a phosphate group, a sugar, and an amino acid.
C.
They are polymers of subunits containing glucose andamino acids.
D.
They are long polymers of amino acids, folded into an alpha helix.
E.
They are polymers of subunits containing a phosphate group, a sugar, and a purine or pyrimidine base.
Question #10
A solution with a pH of 8 is more acidic than one with a pH of 3.
A.
FALSE
B.
TRUE
Question #11
Trace elements such as zinc and manganese are found in minute quantities in the body but do not serve any known function.
A.
TRUE
B.
FALSE
Question #12
Carbon-12 and carbon-14 are isotopes. How are they different from each other?
A.
They can form different numbers of chemical bonds.
B.
They have different numbers of protons.
C.
They have different numbers of electrons.
D.
They have different numbers of neutrons.
E.
They have different number of energy shells
Question #13
If a sports beverage advertises that it replaces the body's electrolytes, what does the drink contain?
A.
Ionic forms of mineral elements
B.
Oxygen and gases used by metabolism
C.
Vitamins
D.
Sugars that were broken down for energy
E.
Lipids that form the membranes of cells
Question #14
The carboxyl ion is an anion.
A.
TRUE
B.
FALSE
Question #15
Cholesterol is a phospholipid.
A.
FALSE
B.
TRUE
Question #16
What are the two main atoms inlipids, and what type of bonds connect them?
A.
Carbon and hydrogen, connected by ionic bonds
B.
Carbon and hydrogen, connected by non-polar covalent bonds
C.
Carbon and hydrogen, connected by hydrogen bonds
D.
Oxygen and hydrogen, connected by hydrogen bonds
E.
Carbon and oxygen, connected by polar covalent bonds.
Question #17
Estrogen is a steroid hormone, therefore it will readily dissolve through a lipid bilayer.
A.
TRUE
B.
FALSE
Question #18
Muscle cell contraction is facilitated by a small electrical current. Which types of molecules are likely involved?
A.
Free radicals
B.
Isotopes
C.
Gasses
D.
Electrolytes
E.
Vitamins
Question #19
Lysosomes are organelles specialized for breaking down intracellular debris or malfunctioning parts of cells.
A.
FALSE
B.
TRUE
Question #20
There are twenty different aminoacyl-tRNA synthetases.
A.
TRUE
B.
FALSE
Question #21
Which best describes functions of thesmooth (agranular)endoplasmic reticulum?
A.
Generation of ATP
B.
Transcription of DNA into RNA
C.
Synthesis of lipids and intracellular storage of calcium ions
D.
Synthesis and packaging of proteins for secretion from the cell or export to other organelles
E.
Digestion of engulfed bacteria and cellular debris
Question #22
Transcription factors activate or repress the transcription of specific genes by binding to regions of DNA that interact with the promoter region of a gene.
A.
TRUE
B.
FALSE
Question #23
Which of the following metabolic pathways can proceed in the absence of oxygen?
A.
Oxidative phosphorylation
B.
Glycolysis
C.
None of the choices are correct.
D.
The breakdown of fatty acids to CO 2 and H 2O
E.
Krebs cycle
Question #24
Macrophages are cells that engulf and digest bacteria and cell debris. To perform the digestive function, macrophages tend to have more __________ than other cells.
A.
mitochondria
B.
lysosomes
C.
endosomes
D.
ribosomes
E.
peroxisomes
Question #25
The promoter sequence of nucleotides in a gene is present on both strands of the DNA molecule, allowing transcription of both strands.
A.
FALSE
B.
TRUE
Question #26
Intracellular fluid is defined as the fluid in the cytosol and organelles.
A.
TRUE
B.
FALSE
Question #27
You are observing the rate of an enzymatic reaction. You continue to add substrate in higher and higher concentrations, but eventually you see the rate of reaction plateau, no further increases in the rate of the reaction could be observed. Which of the following are plausible explanations for your observation (select all that apply)?
A.
The substrate solution has become contaminated with an allosteric inhibitor.
B.
Over time, the substrate molecules are denaturing.
C.
The temperature of the room needs to increase to increase the rate of reaction.
D.
The enzyme has become saturated.
E.
The enzyme molecules are being used up and broken down by the reaction.
Question #28
In a blood cell, water and carbon dioxide can combine in a reversible reaction to form carbonic acid. If the concentration of carbonic acid increases, which direction will the net reaction proceed in?
A.
The net rate will be unaffected by an increase in carbonic acid concentration.
B.
The forward direction (toward more carbonic acid accumulation)
C.
The reverse direction (toward more water and carbon dioxide accumulation)
Question #29
The active site of an enzyme is a functional binding site.
A.
FALSE
B.
TRUE
Question #30
Consider the reaction below, which of the following is TRUE? H2CO3 ↔ CO2 + H2O + 4 kcal/mol.
A.
The reaction is catabolic and the energy content of the products are equal to that of the reactant.
B.
The reaction is anabolic and the energy content of the reactant is greater than that of the products.
C.
The reaction is anabolic and the energy content of the products is greater than that of the reactant.
D.
The reaction is catabolic and the energy content of the products is greater than that of the reactant.
E.
The reaction is catabolic and the energy content of the reactant is greater than that of the products.
Question #31
During a lab experiment, you forgot to label your solution containers. You see that red blood cells were placed into an unlabeled solution and they shrunk. What can be concluded about the unknown solution?
A.
Its penetrating solute concentration is greater than that of a normalcell
B.
Its penetrating solute concentration is less than that of a normalcell.
C.
Its nonpenetrating solute concentration is greater than that of a normalcell.
D.
Its nonpenetrating solute concentration is less than that of a normalcell
E.
Its nonpenetrating solute concentration is equal to that of a normalcell.
Question #32
Which of the following statements regarding the diffusion of a nonpolar solute Xacross a cell membrane is correct?
A.
Solute X will reach equilibrium, but the concentration will be much higher on the inside of the cell because of the smaller volume.
B.
At equilibrium, the netflux of X across the cell membrane is zero.
C.
Solute X will be unable to reach equilibrium because it is nonpolar.
D.
At equilibrium, X will cease movingacross the cell membrane.
E.
At equilibrium, movement of X across the membrane will be much faster in one direction than in the other.
Question #33
In most of the cells in the body there is an electrical difference such that the inside of cells is positive with respect to the outside.
A.
FALSE
B.
TRUE
Question #34
If the ATP-generating mechanisms in a cell are poisoned and the cell depletes its ATP reserves, which would occur first?
A.
diffusion.
B.
apoptosis.
C.
osmosis.
D.
endocytosis.
E.
facilitated diffusion.
Question #35
If the ATP-generating mechanisms in a cell are poisoned and the cell depletes its ATP reserves, which would occur first?
A.
Secondary active transport of molecules would cease
B.
Facilitated diffusion of molecules would cease.
C.
All transport processes would cease immediately when the ATP was depleted.
D.
Primary active transport of molecules would cease.
E.
Ion concentration gradients would reach equilibrium across the cell membrane.
Question #36
In general, polar molecules diffuse more rapidly through the lipid bilayer part of cell membranes than do nonpolar molecules. This statement is
A.
true.
B.
false, because nonpolar molecules diffuse through more rapidly because much of the bilayer is nonpolar.
C.
false, because polar molecules diffuse through less rapidly because the bilayer is nonpolar throughout its width.
D.
false, because the rate of diffusion of nonpolar and polar molecules through the bilayer is essentially the same as long as the molecules are the same size.
E.
false, because polar molecules diffuse through less rapidly because the bilayer is polar throughout its width.
Question #37
Mediated transport is required in order for glucose, amino acids, and fatty acids to pass into cells because none of these substances can diffuse through plasma membranes.
A.
TRUE
B.
FALSE
Question #38
Adding one mole of NaCl to one liter of water will lower the water concentration twice as much as adding one mole of glucose.
A.
FALSE
B.
TRUE
Question #39
Which of the following statements about epithelial cells or epithelial transport is NOT correct?
A.
The plasma membrane of epithelial cells that face the inside of a hollow or fluid-filled chamber in the body is called the basolateral membrane.
B.
The pathway taken by substances that flow between epithelial cells is called the paracellular pathway.
C.
When substances cross epithelial barriers by going through the cell membranes and cytosol, it is called the transcellular pathway.
D.
Epithelial cell membranes express different transport proteins on different cell surfaces.
E.
Epithelial cells lining the small intestine have Na +-K +-ATPase pumps only in their basolateral membranes.
Question #40
The Greater the Concentration Difference of a Substance Between Two Solutions Separated by a Permeable Membrane, the Lesser the Magnitude of the Net Flux of the Substance.
A.
TRUE
B.
FALSE
Question #41
Which of the following is known to be a second messenger?
A.
Adenylyl cyclase
B.
Epinephrine
C.
ATP
D.
Diacylglycerol
E.
Phospholipase C
Question #42
Amplification during a second-messenger cascade is beneficial because amplification
A.
results in the production of more of the first messenger.
B.
allows small amounts of hormones to produce large responses in target cells.
C.
takes small molecules and makes polymers out of them.
D.
allows a cell to respond to more different hormones.
Question #43
An adipose (fat) cell responds to the presence of the hormone epinephrine by increasing cytosolic cyclic AMP production, which leads to the catabolism of both glycogen and fat. What is the most likely explanation for this phenomenon?
A.
Cyclic AMP-dependent protein kinase activates two kinds of enzymes.
B.
Epinephrine is binding to two types of receptors in the plasma membrane.
C.
Cyclic AMP directly activates enzymes that catabolize glycogen and fat.
D.
The activated receptor complex stimulates production of two different second messengers.
Question #44
Designing a drug that blocked the release of eicosanoids would be an effective therapy for both pain and inflammation.
A.
FALSE
B.
TRUE
Question #45
Aspirin and other nonsteroidal anti-inflammatory drugs are more specific in their effects on eicosanoid synthesis than are steroidal anti-inflammatory drugs.
A.
TRUE
B.
FALSE
Question #46
Researchers have found that enkephalin receptors are upregulated in cocaine addicts when compared to non-users. It is likely that the action of cocaine
A.
increases enkephalin in the brain.
B.
is an agonist to the enkephalin receptor.
C.
decreases enkephalin in the brain
D.
increases enkephalin’s affinity for its receptor.
Question #47
Endogenous opioid molecules reduce pain sensation. Morphine, a common analgesic, is an agonist for endogenous opioid receptors.
A.
FALSE
B.
TRUE
Question #48
Which of the following might be phosphorylated in a signaling pathway?
A.
G-protein coupled receptor
B.
cAMP
C.
Enzymes
D.
Tyrosine residues
Question #49
Type 2 diabetes mellitus is a disease in which the effect insulin has on the cell is reduced, despite consistent levels of circulating insulin (in the beginning of the disease). Which of the following could possibly explain this phenomenon?
A.
Decreased expression of the second messenger in the insulin pathway
B.
Downregulation of insulin receptors
C.
Upregulation of insulin receptors
D.
Saturation of the insulin receptor
E.
Increased affinity of insulin for its receptor
Question #50
Drug Y is a drug that is used to increase the force of contraction achieved by heart muscle tissue. In the absence of the drug, epinephrine increases heart contractility through a signaling pathway that involves a receptor and cAMP. Which of the following are plausible mechanisms of action for Y?
A.
Decreasing the activity of cAMP-dependent protein kinase
B.
Increasing the expression of cAMP
C.
Acting as an agonist on the receptor for epinephrine, a hormone that increases heart contractility
D.
Increasing the availability of phosphodiesterase molecules
E.
Inhibiting phosphodiesterase activity
Question #51
The number of distinct cell types in the human body is about twenty.
A.
FALSE
B.
TRUE
Question #52
A person who is acclimated to a hot environment will begin to react physiologically to a decreased environmental temperature faster than a person who is not.
A.
TRUE
B.
FALSE
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