Physiology 001 - Introduction to Human Physiology » Winter 2021 » Lecture Exam 2
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Question #1
Which of the following statements regarding neurotransmitters is TRUE?
A.
Gamma-aminobutyric acid (GABA) is a major excitatory transmitter in the central nervous system.
B.
Catecholamines are the most abundant neurotransmitters in the central nervous system.
C.
Acetylcholine is broken down by enzymes present on postsynaptic cell membranes.
D.
Acetylcholine that is released at synapses binds to adrenergic receptors in the postsynaptic cell membrane.
E.
Opiate drugs, such as morphine, are antagonists of a class of neurotransmitters called endorphins.
Question #2
Although nerve cells in each cerebral hemisphere make connections with other cells in the same hemisphere, there is no crossover of information between the two hemispheres.
A.
FALSE
B.
TRUE
Question #3
You have a patient who severed a spinal nerve in an accident. She will only lose sensory sensation, but all motor innervation to that area will remain intact.
A.
TRUE
B.
FALSE
Question #4
Nicotinic receptors are expressed on skeletal muscle cells. Which of the following would likely be a side-effect of the use of nicotine, an agonist for those receptors?
A.
Drowsiness
B.
Muscle cell twitches (contractions)
C.
Muscle paralysis
D.
Muscle relaxation
E.
None of the answer choices are correct
Question #5
Serotonin
A.
is a catecholamine neurotransmitter.
B.
acts asa neuromodulator.
C.
is a neuropeptide.
D.
has an excitatory effect on pathways that mediate sensations.
E.
has an inhibitory effect on pathways that are involved in the control of muscles.
Question #6
Inside a neuron, calcium binding sites are likely found on
A.
proteins associated with synaptic vesicles.
B.
dyenin proteins.
C.
smooth endoplasmic reticulum.
D.
kinesin proteins.
E.
lysosomal proteins.
Question #7
Whichis most directly responsible for the falling (repolarizing) phase of the action potential?
A.
ATPase destroys the energy supply that was maintaining the action potential at its peak.
B.
The Na +, K + pump restores the ions to their original locations inside and outside of the cell.
C.
The permeability to Na + increases greatly.
D.
Voltage-gated Na + channels are opened.
E.
The permeability to K + increases greatly while that to Na + decreases.
Question #8
The neurons connecting the adrenal medulla to the brain have been severed during surgery. The result will be a significant decrease in parasympathetic signaling.
A.
TRUE
B.
FALSE
Question #9
The actual receptors for hearing are called
A.
somatic receptors.
B.
hair cells.
C.
baroreceptors.
D.
Pacinian corpuscles.
E.
nociceptors.
Question #10
Certain smells can trigger shifts in emotional state (for example, the smell of a familiar place or a loved one’s clothing) because specific olfactory pathways synapse in the __________.
A.
occipital lobes of the cerebral cortex
B.
somatosensory cortex
C.
frontal lobes of the cerebral cortex
D.
temporal lobes of the cerebral cortex
E.
limbic system
Question #11
What category of receptors do Pacinian corpuscles belong to?
A.
Mechanoreceptors
B.
Photoreceptors
C.
Chemoreceptors
D.
Nociceptors
Question #12
If the pH of the vitreous humor decreased, the first cells that would be effected are
A.
ganglion cells.
B.
rod cells.
C.
cone cells.
D.
bipolar cells.
E.
lateral geniculate cells.
Question #13
Which of the following statements related to the"ON pathway" of thevisual system is correct?
A.
Bipolar cells hyperpolarize in the absence of input from photoreceptor cells.
B.
Glutamate receptors on bipolar cells are excitatory.
C.
Bipolar cells fire action potentials only when bright light strikes the photoreceptors linked to them.
D.
Only cones are associated with bipolar cells of the "ON pathway," rods are not.
E.
Bipolar cells spontaneously depolarize in the absence of input from photoreceptor cells.
Question #14
In the visual pathway providing sensory action potentials to the brain, the first cells that are capable of initiating action potentials are
A.
ganglion cells.
B.
lateral geniculate cells.
C.
cone cells.
D.
rod cells.
E.
bipolar cells.
Question #15
The phenomenon of referred pain may occur because an ascending pathway for pain receives input from both visceral and somatic afferent fibers.
A.
TRUE
B.
FALSE
Question #16
In an individual with macular degeneration, night vision would be impaired.
A.
FALSE
B.
TRUE
Question #17
The EEG tracing of a relaxed individual who has closed eyes and is not concentrating on anything in particular is mainly an alpha rhythm.
A.
FALSE
B.
TRUE
Question #18
Sleep-wake cycles are produced by interactions of nuclei in the brainstem.
A.
TRUE
B.
FALSE
Question #19
During paradoxical sleep
A.
skeletal muscle tension is dramatically increased.
B.
skeletal muscle tension is dramatically increased, brain oxygen consumption is lower than when awake, brain neurotransmitter activity in the pathways regulating states of consciousness is similar to that in the awake state and the person is easily aroused
C.
brain neurotransmitter activity in the pathways regulating states of consciousness is similar to that in the awake state.
D.
brain oxygen consumption is lower than when awake.
E.
the person is easily aroused.
Question #20
Habituation to a stimulus
A.
is due to receptor fatigue.
B.
is due to denaturation of the receptor.
C.
can be overcome by a stronger stimulus of the same type.
D.
is permanent.
E.
is a result of decreased neurotransmitter release secondary to decreased calcium influx at synaptic terminals.
Question #21
Which of the following statements regarding higher brain functions is true?
A.
Both "a person with damage only to Broca's area of the brain will understand spoken or written speech but will have difficulty speaking" and "a person with damage only to Wernicke's area of the brain will have motor aphasia" are true.
B.
Both "a person with damage only to Broca's area of the brain will understand spoken or written speech but will have difficulty speaking" and "a person with damage only to Wernicke's area of the brain will lose the ability to recognize faces" are true.
C.
A person with damage only to Wernicke's area of the brain will have motor aphasia.
D.
A person with damage only to Broca's area of the brain will understand spoken or written speech but will have difficulty speaking.
E.
A person with damage only to Wernicke's area of the brain will lose the ability to recognize faces.
Question #22
Rapid eye movement is descriptive of or occurs during
A.
slow-wave sleep.
B.
paradoxical sleep.
C.
both slow-wave sleep and paradoxical sleep.
D.
neither slow-wave sleep nor paradoxical sleep.
Question #23
You are the technician running the fMRI (functional magentic resonance imaging) machine today. You have had a patient in the machine for quite a while when you notice a sudden change in electrical activity within the RAS. What might be happening?
A.
She is talking.
B.
She is thinking about food.
C.
She has opened her eyes and is taking in visual information.
D.
She is moving.
E.
She fell asleep.
Question #24
Dreaming occurs when one is in NREM sleep.
A.
FALSE
B.
TRUE
Question #25
Multiunit smooth muscle cells
A.
can only be excited, and not inhibited.
B.
have many gap junctions between cells.
C.
respond to stretch by relaxing.
D.
have abundant T-tubules.
E.
generally have individual innervation of each cell.
Question #26
Sarah is a girl with dreams of becoming an Olympic marathon runner. She just learned that she has a rare genetic mutation and does not produce functional creatine phosphate. What portion of Sarah’s marathon experience will be effected?
A.
No effects on her running
B.
Every moment of Sarah’s runs
C.
All muscle contractions after Sarah reaches fatigue (about an hour into her run)
D.
All muscle contractions after Sarah reaches her maximum heart rate (about 10 minutes into her run)
E.
Just the first few seconds of exercise
Question #27
If you tagged all ATPase enzymes in the muscle cell with fluorescent dye you would see tagging on both myosin and on the surface of the sarcoplasmic reticulum.
A.
FALSE
B.
TRUE
Question #28
What is the function of the transverse tubules in a skeletal muscle fiber?
A.
They allow action potentials to propagate deep into the center of skeletal muscle cells.
B.
They manufacture and store ATP.
C.
They form the Z lines that mark the end of each sarcomere.
D.
They run in parallel with the myofibrils, and have abundant Ca 2+-ATPase proteins for pumping Ca 2+ back into the sarcoplasmic reticulum.
E.
They store the calcium ions that are the main source of activation for the cross-bridge cycle.
Question #29
A Ca 2+-binding protein in smooth muscle is calmodulin.
A.
FALSE
B.
TRUE
Question #30
The binding of ATP to myosin causes an allosteric change in myosin's actin-binding site such that the affinity of myosin for actin is decreased.
A.
FALSE
B.
TRUE
Question #31
In skeletal muscle cells, calcium initiates contraction by binding to
A.
the thick filament.
B.
troponin.
C.
tropomyosin.
D.
actin.
E.
myosin.
Question #32
During an isometric twitch in a skeletal muscle
A.
H zones shorten.
B.
the whole muscle shortens.
C.
tetanus occurs.
D.
sarcomeres do not significantly shorten.
E.
tension generated by the muscle always exceeds the load on the muscle.
Question #33
Ouch! You accidentally touched a hot pan on the stove and pull your hand away quickly. Physiologically speaking, what just occurred?
A.
A nociceptor initiated muscle spindle fibers.
B.
A nociceptor stimulated contraction of the contralateral flexor muscle and inhibits contraction of the contralateral extensor muscle.
C.
An afferent neuron sent a signal in a monosynaptic reflex arc.
D.
A nociceptor stimulated the local Golgi tendon organ.
E.
A nociceptor stimulated contraction of the ipsilateral flexor muscle and inhibited contraction of the ipsilateral extensor muscle.
Question #34
Which is TRUE about the function of the cerebellum?
A.
It is important in maintaining posture.
B.
It helps to coordinate body movements.
C.
It stores the memory of motor movements that involve several joints.
D.
It helps to coordinate body movements. It is important in maintaining posture. It receives input from sensory pathways. It stores the memory of motor movements that involve several joints.
E.
It receives input from sensory pathways.
Question #35
The thalamus is an important relay station for feedback of information to the basal nuclei from the motor cortex.
A.
TRUE
B.
FALSE
Question #36
Inhibitory input to motor neurons is as important for normal muscle function as excitatory input.
A.
FALSE
B.
TRUE
Question #37
A.
When stimulated to fire, they always inhibit flexor muscles.
B.
They function to maintain tension on spindle receptors.
C.
Their contraction is stimulated by alpha motor neurons and inhibited by gamma motor neurons.
D.
They are innervated by alpha motor neurons.
E.
They are not true muscle fibers because they cannot contract.
Question #38
When a person steps on a piece of glass with their right foot, flexor muscles on the left leg and extensor muscles on the right leg will be stimulated to contract.
A.
TRUE
B.
FALSE
Question #39
Which of the following normally occurs when a doctor's reflex hammer taps a patient's patellar tendon?
A.
Inhibitory interneurons reduce action potential firing in alpha motor neuronsto extrafusal fibers of extensor muscles.
B.
Alpha motor neurons stimulate contraction of intrafusal fibers in extensor muscles.
C.
Golgi tendon organs in the patellar tendon stimulate the contraction of extrafusal fibers of extensor muscles.
D.
Alpha motor neurons that innervate ipsilateral flexor muscles are stimulated.
E.
Alpha motor neurons stimulate contraction of extrafusal fibers in extensor muscles.
Question #40
The corticospinal pathways
A.
are composed of alpha motor neurons.
B.
are descending motor pathways.
C.
consist of many interneurons linked synaptically.
D.
bring sensory information from the spinal cord to the somatosensory region of the cerebral cortex.
E.
begin in the cortex of the cerebellum.
Question #41
Sally is a 10-year-old girl going through a growth spurt. Her blood levels of growth hormone are two-fold higher than at the same time last week. Which other hormones are likely to also be elevated?
A.
Cortisol
B.
Insulin-like growth factor 1
C.
Follicle-stimulating hormone
D.
Prolactin
E.
ACTH
Question #42
Which is afunction of the gonadotropic hormones?
A.
Stimulating the release of gonadotropin-releasing hormone (GnRH)
B.
Inhibiting the release of prolactin
C.
Inducing the secretion of steroid hormones by the gonads in both males and females
D.
Inhibiting the release of growth hormone
E.
Stimulating the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH)
Question #43
A patient with low circulating androgen levels may have experienced damage to the adrenal gland.
A.
FALSE
B.
TRUE
Question #44
The net intake and output of calcium for the entire body is regulated most directly by the activities of the kidneys and the gastrointestinal tract.
A.
TRUE
B.
FALSE
Question #45
In what form is the body's largest pool of calcium?
A.
Embedded in collagen in many types of connective tissue
B.
Bones, in the form of hydroxyapatites
C.
Liver, inside the endoplasmic reticulum
D.
Skeletal muscle, stored in terminal cisternae
E.
Blood, dissolved within the plasma
Question #46
In a hypothetical rare genetic disease in which the ribosomes in some cells of the anterior pituitary are malformed. Which hormone, if any, would you expect missing from a patient with this disease?
A.
Oxytocin
B.
Thyroid hormone
C.
Estrogen
D.
Growth hormone
E.
Progesterone
Question #47
You have discovered a novel steroid hormone. You’d like to isolate its receptor as part of your next project. Where should you look first?
A.
Any of these might be places where the receptor could be found.
B.
On the cell surface
C.
In the cytoplasm
D.
In the blood stream
Question #48
You are designing an experiment to quantify the levels of stress experienced by different individuals. Which of the following tests would reveal insight as to a patient's chronic stress?
A.
Testing plasma levels of parathyroid hormone
B.
Testing plasma levels of cortisol
C.
Testing plasma levels of dopamine
D.
Testing plasma levels of follicle-stimulating hormone
E.
Testing plasma levels of growth hormone
Question #49
Steroid hormones are stored in the cells that synthesize them until a stimulus is received that provokes their secretion.
A.
TRUE
B.
FALSE
Question #50
If the pituitary gland is removed from a human subject, which of the following is likely to occur?
A.
The adrenal gland will atrophy and plasma cortisol levels will be reduced.
B.
The hypothalamus will secrete less CRH.
C.
The subject will remain euthyroid.
D.
The adrenal gland will hypertrophy to increase cortisol production.
E.
There will be increased negative feedback on growth hormone by insulin-like growth factor 1 (IGF-1).
Question #51
Deficiency of iodine in the diet results in __________ caused by __________.
A.
atrophy of the thyroid gland; loss ofnegative feedback by thyroid hormones and increased thyroid-stimulating hormone (TSH) levels
B.
C.
atrophy of the thyroid gland; decreased sensitivity of receptors for thyroid-stimulating hormone (TSH)
D.
a goiter; loss of negative feedback by thyroid hormones and increased thyroid-stimulating hormone (TSH) levels
E.
a goiter; increased production of thyroid-stimulating hormone (TSH) and increased thyroid hormone levels
F.
atrophy of the anterior pituitary gland; loss of negative feedback by thyroid hormones
Question #52
The primary function of thyrotropin is to stimulate secretion of thyroid hormones.
A.
TRUE
B.
FALSE
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