Physiology 001 - Introduction to Human Physiology » Winter 2021 » Lecture Exam 2
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Question #1
Which of the following statements regarding neurotransmitters is TRUE?
A.
Catecholamines are the most abundant neurotransmitters in the central nervous system.
B.
Opiate drugs, such as morphine, are antagonists of a class of neurotransmitters called endorphins.
C.
Acetylcholine is broken down by enzymes present on postsynaptic cell membranes.
D.
Acetylcholine that is released at synapses binds to adrenergic receptors in the postsynaptic cell membrane.
E.
Gamma-aminobutyric acid (GABA) is a major excitatory transmitter in the central nervous system.
Question #2
Although nerve cells in each cerebral hemisphere make connections with other cells in the same hemisphere, there is no crossover of information between the two hemispheres.
A.
TRUE
B.
FALSE
Question #3
You have a patient who severed a spinal nerve in an accident. She will only lose sensory sensation, but all motor innervation to that area will remain intact.
A.
TRUE
B.
FALSE
Question #4
Nicotinic receptors are expressed on skeletal muscle cells. Which of the following would likely be a side-effect of the use of nicotine, an agonist for those receptors?
A.
Muscle cell twitches (contractions)
B.
None of the answer choices are correct
C.
Drowsiness
D.
Muscle relaxation
E.
Muscle paralysis
Question #5
Serotonin
A.
has an inhibitory effect on pathways that are involved in the control of muscles.
B.
is a neuropeptide.
C.
has an excitatory effect on pathways that mediate sensations.
D.
acts asa neuromodulator.
E.
is a catecholamine neurotransmitter.
Question #6
Inside a neuron, calcium binding sites are likely found on
A.
lysosomal proteins.
B.
dyenin proteins.
C.
proteins associated with synaptic vesicles.
D.
kinesin proteins.
E.
smooth endoplasmic reticulum.
Question #7
Whichis most directly responsible for the falling (repolarizing) phase of the action potential?
A.
The permeability to K + increases greatly while that to Na + decreases.
B.
Voltage-gated Na + channels are opened.
C.
The permeability to Na + increases greatly.
D.
ATPase destroys the energy supply that was maintaining the action potential at its peak.
E.
The Na +, K + pump restores the ions to their original locations inside and outside of the cell.
Question #8
The neurons connecting the adrenal medulla to the brain have been severed during surgery. The result will be a significant decrease in parasympathetic signaling.
A.
TRUE
B.
FALSE
Question #9
The actual receptors for hearing are called
A.
hair cells.
B.
Pacinian corpuscles.
C.
nociceptors.
D.
somatic receptors.
E.
baroreceptors.
Question #10
Certain smells can trigger shifts in emotional state (for example, the smell of a familiar place or a loved one’s clothing) because specific olfactory pathways synapse in the __________.
A.
temporal lobes of the cerebral cortex
B.
frontal lobes of the cerebral cortex
C.
limbic system
D.
somatosensory cortex
E.
occipital lobes of the cerebral cortex
Question #11
What category of receptors do Pacinian corpuscles belong to?
A.
Photoreceptors
B.
Chemoreceptors
C.
Nociceptors
D.
Mechanoreceptors
Question #12
If the pH of the vitreous humor decreased, the first cells that would be effected are
A.
bipolar cells.
B.
rod cells.
C.
ganglion cells.
D.
cone cells.
E.
lateral geniculate cells.
Question #13
Which of the following statements related to the"ON pathway" of thevisual system is correct?
A.
Bipolar cells fire action potentials only when bright light strikes the photoreceptors linked to them.
B.
Only cones are associated with bipolar cells of the "ON pathway," rods are not.
C.
Bipolar cells spontaneously depolarize in the absence of input from photoreceptor cells.
D.
Glutamate receptors on bipolar cells are excitatory.
E.
Bipolar cells hyperpolarize in the absence of input from photoreceptor cells.
Question #14
In the visual pathway providing sensory action potentials to the brain, the first cells that are capable of initiating action potentials are
A.
bipolar cells.
B.
ganglion cells.
C.
lateral geniculate cells.
D.
rod cells.
E.
cone cells.
Question #15
The phenomenon of referred pain may occur because an ascending pathway for pain receives input from both visceral and somatic afferent fibers.
A.
TRUE
B.
FALSE
Question #16
In an individual with macular degeneration, night vision would be impaired.
A.
TRUE
B.
FALSE
Question #17
The EEG tracing of a relaxed individual who has closed eyes and is not concentrating on anything in particular is mainly an alpha rhythm.
A.
TRUE
B.
FALSE
Question #18
Sleep-wake cycles are produced by interactions of nuclei in the brainstem.
A.
FALSE
B.
TRUE
Question #19
During paradoxical sleep
A.
skeletal muscle tension is dramatically increased, brain oxygen consumption is lower than when awake, brain neurotransmitter activity in the pathways regulating states of consciousness is similar to that in the awake state and the person is easily aroused
B.
the person is easily aroused.
C.
brain neurotransmitter activity in the pathways regulating states of consciousness is similar to that in the awake state.
D.
brain oxygen consumption is lower than when awake.
E.
skeletal muscle tension is dramatically increased.
Question #20
Habituation to a stimulus
A.
is due to receptor fatigue.
B.
is permanent.
C.
is a result of decreased neurotransmitter release secondary to decreased calcium influx at synaptic terminals.
D.
can be overcome by a stronger stimulus of the same type.
E.
is due to denaturation of the receptor.
Question #21
Which of the following statements regarding higher brain functions is true?
A.
A person with damage only to Wernicke's area of the brain will have motor aphasia.
B.
Both "a person with damage only to Broca's area of the brain will understand spoken or written speech but will have difficulty speaking" and "a person with damage only to Wernicke's area of the brain will have motor aphasia" are true.
C.
Both "a person with damage only to Broca's area of the brain will understand spoken or written speech but will have difficulty speaking" and "a person with damage only to Wernicke's area of the brain will lose the ability to recognize faces" are true.
D.
A person with damage only to Wernicke's area of the brain will lose the ability to recognize faces.
E.
A person with damage only to Broca's area of the brain will understand spoken or written speech but will have difficulty speaking.
Question #22
Rapid eye movement is descriptive of or occurs during
A.
paradoxical sleep.
B.
slow-wave sleep.
C.
both slow-wave sleep and paradoxical sleep.
D.
neither slow-wave sleep nor paradoxical sleep.
Question #23
You are the technician running the fMRI (functional magentic resonance imaging) machine today. You have had a patient in the machine for quite a while when you notice a sudden change in electrical activity within the RAS. What might be happening?
A.
She is thinking about food.
B.
She is talking.
C.
She fell asleep.
D.
She is moving.
E.
She has opened her eyes and is taking in visual information.
Question #24
Dreaming occurs when one is in NREM sleep.
A.
FALSE
B.
TRUE
Question #25
Multiunit smooth muscle cells
A.
generally have individual innervation of each cell.
B.
respond to stretch by relaxing.
C.
can only be excited, and not inhibited.
D.
have abundant T-tubules.
E.
have many gap junctions between cells.
Question #26
Sarah is a girl with dreams of becoming an Olympic marathon runner. She just learned that she has a rare genetic mutation and does not produce functional creatine phosphate. What portion of Sarah’s marathon experience will be effected?
A.
Just the first few seconds of exercise
B.
All muscle contractions after Sarah reaches fatigue (about an hour into her run)
C.
All muscle contractions after Sarah reaches her maximum heart rate (about 10 minutes into her run)
D.
Every moment of Sarah’s runs
E.
No effects on her running
Question #27
If you tagged all ATPase enzymes in the muscle cell with fluorescent dye you would see tagging on both myosin and on the surface of the sarcoplasmic reticulum.
A.
FALSE
B.
TRUE
Question #28
What is the function of the transverse tubules in a skeletal muscle fiber?
A.
They manufacture and store ATP.
B.
They form the Z lines that mark the end of each sarcomere.
C.
They allow action potentials to propagate deep into the center of skeletal muscle cells.
D.
They run in parallel with the myofibrils, and have abundant Ca 2+-ATPase proteins for pumping Ca 2+ back into the sarcoplasmic reticulum.
E.
They store the calcium ions that are the main source of activation for the cross-bridge cycle.
Question #29
A Ca 2+-binding protein in smooth muscle is calmodulin.
A.
FALSE
B.
TRUE
Question #30
The binding of ATP to myosin causes an allosteric change in myosin's actin-binding site such that the affinity of myosin for actin is decreased.
A.
TRUE
B.
FALSE
Question #31
In skeletal muscle cells, calcium initiates contraction by binding to
A.
troponin.
B.
the thick filament.
C.
actin.
D.
tropomyosin.
E.
myosin.
Question #32
During an isometric twitch in a skeletal muscle
A.
tension generated by the muscle always exceeds the load on the muscle.
B.
sarcomeres do not significantly shorten.
C.
tetanus occurs.
D.
H zones shorten.
E.
the whole muscle shortens.
Question #33
Ouch! You accidentally touched a hot pan on the stove and pull your hand away quickly. Physiologically speaking, what just occurred?
A.
A nociceptor stimulated contraction of the ipsilateral flexor muscle and inhibited contraction of the ipsilateral extensor muscle.
B.
A nociceptor initiated muscle spindle fibers.
C.
A nociceptor stimulated the local Golgi tendon organ.
D.
A nociceptor stimulated contraction of the contralateral flexor muscle and inhibits contraction of the contralateral extensor muscle.
E.
An afferent neuron sent a signal in a monosynaptic reflex arc.
Question #34
Which is TRUE about the function of the cerebellum?
A.
It helps to coordinate body movements. It is important in maintaining posture. It receives input from sensory pathways. It stores the memory of motor movements that involve several joints.
B.
It receives input from sensory pathways.
C.
It helps to coordinate body movements.
D.
It stores the memory of motor movements that involve several joints.
E.
It is important in maintaining posture.
Question #35
The thalamus is an important relay station for feedback of information to the basal nuclei from the motor cortex.
A.
TRUE
B.
FALSE
Question #36
Inhibitory input to motor neurons is as important for normal muscle function as excitatory input.
A.
FALSE
B.
TRUE
Question #37
A.
Their contraction is stimulated by alpha motor neurons and inhibited by gamma motor neurons.
B.
They are innervated by alpha motor neurons.
C.
They are not true muscle fibers because they cannot contract.
D.
When stimulated to fire, they always inhibit flexor muscles.
E.
They function to maintain tension on spindle receptors.
Question #38
When a person steps on a piece of glass with their right foot, flexor muscles on the left leg and extensor muscles on the right leg will be stimulated to contract.
A.
TRUE
B.
FALSE
Question #39
Which of the following normally occurs when a doctor's reflex hammer taps a patient's patellar tendon?
A.
Golgi tendon organs in the patellar tendon stimulate the contraction of extrafusal fibers of extensor muscles.
B.
Alpha motor neurons stimulate contraction of extrafusal fibers in extensor muscles.
C.
Alpha motor neurons stimulate contraction of intrafusal fibers in extensor muscles.
D.
Alpha motor neurons that innervate ipsilateral flexor muscles are stimulated.
E.
Inhibitory interneurons reduce action potential firing in alpha motor neuronsto extrafusal fibers of extensor muscles.
Question #40
The corticospinal pathways
A.
consist of many interneurons linked synaptically.
B.
are descending motor pathways.
C.
begin in the cortex of the cerebellum.
D.
are composed of alpha motor neurons.
E.
bring sensory information from the spinal cord to the somatosensory region of the cerebral cortex.
Question #41
Sally is a 10-year-old girl going through a growth spurt. Her blood levels of growth hormone are two-fold higher than at the same time last week. Which other hormones are likely to also be elevated?
A.
Insulin-like growth factor 1
B.
ACTH
C.
Cortisol
D.
Follicle-stimulating hormone
E.
Prolactin
Question #42
Which is afunction of the gonadotropic hormones?
A.
Inducing the secretion of steroid hormones by the gonads in both males and females
B.
Inhibiting the release of prolactin
C.
Stimulating the release of gonadotropin-releasing hormone (GnRH)
D.
Inhibiting the release of growth hormone
E.
Stimulating the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH)
Question #43
A patient with low circulating androgen levels may have experienced damage to the adrenal gland.
A.
TRUE
B.
FALSE
Question #44
The net intake and output of calcium for the entire body is regulated most directly by the activities of the kidneys and the gastrointestinal tract.
A.
FALSE
B.
TRUE
Question #45
In what form is the body's largest pool of calcium?
A.
Liver, inside the endoplasmic reticulum
B.
Embedded in collagen in many types of connective tissue
C.
Bones, in the form of hydroxyapatites
D.
Blood, dissolved within the plasma
E.
Skeletal muscle, stored in terminal cisternae
Question #46
In a hypothetical rare genetic disease in which the ribosomes in some cells of the anterior pituitary are malformed. Which hormone, if any, would you expect missing from a patient with this disease?
A.
Oxytocin
B.
Estrogen
C.
Thyroid hormone
D.
Growth hormone
E.
Progesterone
Question #47
You have discovered a novel steroid hormone. You’d like to isolate its receptor as part of your next project. Where should you look first?
A.
In the cytoplasm
B.
Any of these might be places where the receptor could be found.
C.
On the cell surface
D.
In the blood stream
Question #48
You are designing an experiment to quantify the levels of stress experienced by different individuals. Which of the following tests would reveal insight as to a patient's chronic stress?
A.
Testing plasma levels of dopamine
B.
Testing plasma levels of cortisol
C.
Testing plasma levels of follicle-stimulating hormone
D.
Testing plasma levels of growth hormone
E.
Testing plasma levels of parathyroid hormone
Question #49
Steroid hormones are stored in the cells that synthesize them until a stimulus is received that provokes their secretion.
A.
TRUE
B.
FALSE
Question #50
If the pituitary gland is removed from a human subject, which of the following is likely to occur?
A.
The adrenal gland will hypertrophy to increase cortisol production.
B.
The adrenal gland will atrophy and plasma cortisol levels will be reduced.
C.
There will be increased negative feedback on growth hormone by insulin-like growth factor 1 (IGF-1).
D.
The hypothalamus will secrete less CRH.
E.
The subject will remain euthyroid.
Question #51
Deficiency of iodine in the diet results in __________ caused by __________.
A.
atrophy of the anterior pituitary gland; loss of negative feedback by thyroid hormones
B.
a goiter; loss of negative feedback by thyroid hormones and increased thyroid-stimulating hormone (TSH) levels
C.
atrophy of the thyroid gland; decreased sensitivity of receptors for thyroid-stimulating hormone (TSH)
D.
atrophy of the thyroid gland; loss ofnegative feedback by thyroid hormones and increased thyroid-stimulating hormone (TSH) levels
E.
a goiter; increased production of thyroid-stimulating hormone (TSH) and increased thyroid hormone levels
F.
Question #52
The primary function of thyrotropin is to stimulate secretion of thyroid hormones.
A.
TRUE
B.
FALSE
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