Chem 40005 - Clinical Chemistry » Summer 2021 » Module 8 Quiz
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Question #1
The use of the urea breath test for detection of H. pylori involves
A.
production of hydrogen by bacterial metabolism that is absorbed into the systemic circulation and exhaled in the breath as urea.
B.
titration of bacterial free acid in breath with sodium hydroxide to a pH end point of 3.5 compared with a urea standard.
C.
immunoassay measurement of deficiency of IgA-class transglutaminase in breath using tissue transglutaminase as an antigen.
D.
bacterial hydrolysis of ingested labeled urea producing labeled bicarbonate, which is absorbed into the blood and exhaled as 14CO2 or 13CO2.
Question #2
An autoimmune disorder produced by ingestion of gluten and characterized by inflammatory damage to intestinal lining cells and malabsorption is
A.
Crohn’s disease.
B.
celiac disease.
C.
ulcerative colitis.
D.
lactose intolerance.
Question #3
Chronic pancreatic damage leads to pancreatic insufficiency. In children, this is most commonly associated with
A.
accidental alcohol ingestion.
B.
gallstones.
C.
cystic fibrosis.
D.
pancreatic tumors.
Question #4
During the gastric phase of the digestive process, HCl will be released from parietal cells following the _____ of gastrin from the mucosal endocrine cells in the stomach.
A.
release
B.
inhibition
Question #5
Which one of the following peptide hormones acts to increase intestinal motility and stimulate gallbladder contractions?
A.
Secretin
B.
Insulin
C.
Cholecystokinin (CCK)
D.
Glucagon
Question #6
Regarding the gastrointestinal (GI) tract, the function of gastrin is to
A.
regulate contraction of the gallbladder.
B.
stimulate intestinal motility.
C.
induce absorption of digested food products across the intestinal wall.
D.
stimulate release of GI hormones, such as secretin and insulin.
Question #7
A peptide secreted by the upper intestinal mucosa that causes gallbladder contraction and release of digestive enzymes from the pancreas, and is also localized in the nervous system, is
A.
VIP.
B.
CCK.
C.
secretin.
D.
insulin.
Question #8
The clinical usefulness of calcitonin measurement is
A.
in the assessment of primary hyperparathyroidism.
B.
as a tumor marker for medullary thyroid carcinoma.
C.
the differential diagnosis of multiple endocrine neoplasia (MEN).
D.
in the determination of sources of vitamin D deficiency.
Question #9
Which one of the following diseases is characterized by a loss in bone mass?
A.
Osteoporosis
B.
Osteomalacia
C.
Bone cancer
D.
Rickets
Question #10
Rickets is sometimes associated with deficiency of which one of the following vitamins?
A.
C
B.
B12
C.
A
D.
D
Question #11
What makes up the organic matrix component of bone?
A.
Minerals and cells only
B.
Type I collagen and noncollagenous proteins
C.
Cells only
D.
Cells and collagen only
Question #12
In a case of osteomalacia related to vitamin D deficiency, would serum calcium be increased, decreased, or remain unchanged?
A.
Increased
B.
Decreased
C.
Remain unchanged
Question #13
Telopeptides
A.
are enzymes that become elevated during bone growth.
B.
are released from type I collagen during bone resorption.
C.
is the most abundant noncollagenous protein in bone.
D.
are bone collagen degradation products whose serum level can reflect bone formation.
Question #14
The primary physiological regulator of parathyroid hormone (PTH) synthesis and secretion is
A.
the concentration of PTH in blood.
B.
PTH stimulating hormone.
C.
the concentration of free calcium in blood or extracellular fluid.
D.
PTH releasing hormone from the pituitary gland.
Question #15
Thyroid hormones are derived from the amino acid
A.
theophylline.
B.
phenylalanine.
C.
threonine.
D.
tyrosine.
Question #16
Regarding thyroid hormones, the primary secretory product of the normal thyroid gland is in the form of
A.
thyroglobulin (Tg).
B.
iodine.
C.
free thyroxine (T4).
D.
free triiodothyronine (T3).
Question #17
The limited clinical information that is available from the results of a total T4 measurement is due to
A.
the fact that total T4 measurements reflect inactive, protein-bound hormone.
B.
the formation of fibrin clots during the preparation of the blood sample.
C.
the fact that circadian rhythms are not determined.
D.
interferences with circulating autoantibodies directed against the colloid.
Question #18
Thyroid-stimulating hormone (TSH) receptor antibodies can be detected in serum of patients having which of the following?
A.
Multinodular goiter
B.
Graves’ disease
C.
Thyroid tumors
D.
Thyrotoxicosis
Question #19
The secretory unit of the thyroid gland is the
A.
parafollicular cell.
B.
colloid.
C.
thymus.
D.
thyroid follicle.
Question #20
Increased TSH, decreased T3, and decreased T4 with the presence of goiter indicate
A.
tertiary hypothyroidism.
B.
pseudohypothyroidism.
C.
primary hypothyroidism.
D.
secondary hypothyroidism.
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