Biol 303 - Intermediate Cell Biology » Fall 2021 » Exam 1 Fast Facts

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Question #1
An organism like a Paramecium has contractile vacuoles to continually eliminate from the cell water that has leaked in by osmosis. Thus, the water environment in which this organism lives is
A.   None of these statements is correct
B.   hypertonic to Paramecium
C.   isotonic to Paramecium
D.   hypotonic to Paramecium
Question #2
Which of the following is true about the cholesterol associated with membranes?
A.   It is oriented with the small hydroxyl group embedded in the lipid bilayer and the remainder of the molecule toward the membrane surface.
B.   All of these statements are correct
C.   It interferes with the movements of the fatty acid tails of the phospholipids.
D.   It makes the cell membrane fluid at room temperature.
Question #3
Which of the following crosses lipid bilayers the fastest?
A.   a small, nonpolar molecule like oxygen (O2)
B.   a small, polar molecule like water
C.   a sodium ion
D.   a large, polar molecule like glucose
Question #4
How do cells transport small, lipid-soluble molecules across the cell membrane?
A.   Via aquaporin channels.
B.   Via active transport.
C.   Such molecules diffuse freely.
D.   Through facilitated diffusion.
Question #5
Which of the following increases the strength of the hydrophobic interactions in lipid bilayers and thus makes them less permeable to polar molecules?
A.   increasing length of the hydrocarbon chains
B.   increasing temperature
C.   the presence of double bonds in fatty acid chains
D.   removing cholesterol
Question #6
Diffusion during which the substance to be transported binds selectively to a membrane-spanning protein, which helps the process along, is called
A.   simple diffusion
B.   osmosis
C.   facilitated osmosis
D.   active transport
E.   facilitated diffusion
Question #7
Which of the following compounds can diffuse across a phospholipid bilayer by themselves?
A.   Ca2+
B.   water
C.   glucose
D.   water, glucose and Ca2+
Question #8
A person is sailing in the ocean and decides to drink some of the seawater. What kind of problem might this person end up having?
A.   Dehydration
B.   High blood pressure
C.   Cell lysis
D.   None of these.
Question #9
Transporters in the membrane undergo transitions between different conformations depending on whether the substrate-binding pocket is empty or occupied.
A.   TRUE
B.   FALSE
Question #10
Membranes contain a wide diversity of lipids, including
A.   triglycerides, cholesterol and phosphoglycerides
B.   phosphoglycerides, sphingolipids and triglycerides
C.   cholesterol, triglycerides and sphingolipids
D.   cholesterol, phosphoglycerides and sphingolipids
Question #11
Most of the functions of a cell membrane are performed by
A.   cholesterol
B.   proteins
C.   triglycerides
D.   glycolipids
Question #12
What level of structure in proteins is held together by R group interactions between different polypeptides?
A.   quarternary structure
B.   tertiary structure
C.   secondary structure
D.   primary structure
Question #13
Structure plays a role in protein function but does not play a role in carbohydrate function.
A.   TRUE
B.   FALSE
Question #14
Which of the following statements about hydrogen bonds is true?
A.   They can occur between most polar molecules.
B.   They can be found between the two strands of a DNA molecule, occur between most polar molecules and are weak attractive interactions
C.   They can be found between the two strands of a DNA molecule.
D.   They are weak attractive interactions
Question #15
Molecular chaperones are “helper proteins” to prevent nonselective interactions during protein folding in order to achieve proper 3D conformation.
A.   TRUE
B.   FALSE
Question #16
The use of hydrogen bonds to make alpha helices and beta sheets is what level of protein folding.
A.   Secondary
B.   Primary
Question #17
Which interaction is most important in enhancing the solubility of macromolecules in water?
A.   hydrophobic interactions
B.   nonpolar covalent bonds
C.   van der Waals forces
D.   Both hydrophobic interactions and nonpolar covalent bonds
E.   hydrogen bonds
Question #18
Proteins are often composed of two or more distinct modules that fold up independently of one another. They often represent parts of a protein that function in a semi-independent manner. These modules are called
A.   protein motifs
B.   functional groups
C.   domains
D.   quaternary structure motifs
Question #19
Denaturation of a protein is due to the breaking of all covalent and non-covalent bonds in order to unfold a protein.
A.   FALSE
B.   TRUE
Question #20
Where are hydrophobic interactions most likely to occur?
A.   between two charged molecules
B.   the core of a water-soluble protein
C.   in contact with water molecules
D.   between two ions
E.   on the surface of a water-soluble protein
Question #21
A disruption of all non-covalent bonds leading to protein loss of function is called what?
A.   Denatured
B.   Natured
Question #22
Identify the technique: Method to separate cell components into fractions.
A.   Differential Centrifugation
B.   Differential Rotation
Question #23
Why are proteins separated on an SDS polyacrylamide gel equally attracted to the positive electrode?
A.   They carry a relatively uniform positive charge distribution.
B.   They are all the same size.
C.   They carry a relatively uniform negative charge distribution.
D.   They are all the same molecular weight.
E.   They all have the same degree of hydrophobicity.
Question #24
Which of these is not part of cell theory?
A.   Cells arise by division of a pre-existing cell
B.   All organisms are composed of one or more cells.
C.   Cells contain genetic information in the form of RNA that is passed to the next cell generation
D.   The cell is the structural unit of life
Question #25
What is true about cells grown in culture?
A.   All cells in culture must be able to evolve and cultured cells are not used often by cell biologists.
B.   HeLa cells are cultured tumor cells isolated from a cancer patient and used by pharmaceutical companies without permission and cells can grow and reproduce in culture for extended periods.
C.   Cultured cells are not used often by cell biologists and cells can grow and reproduce in culture for extended periods.
D.   All cells in culture must be able to evolve and heLa cells are cultured tumor cells isolated from a cancer patient and used by pharmaceutical companies without permission and cells can grow and reproduce in culture for extended periods.
Question #26
Cell size is limited by the fact that its ability to exchange nutrients is proportional to its surface area.
A.   FALSE
B.   TRUE

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