A.   ABCB6 can be identified in exosomes of red blood cells and glycosylation of ABCB6 protein directs it to the mitochondria

B.   ABCB6 appears to be responsible for mitochondria uptake of porphyrins and glycosylation of ABCB6 protein directs it to the mitochondria

C.   ABCB6 can be identified in exosomes of red blood cells, ABCB6 protein is found in the plasma membrane of red blood cells and the location of three other ABC proteins (7, 8 and 10), was confirmed to be localized to the mitochondria membrane

A.   Figure 4 showing ABCB6 staining associated with human reticulocytes

B.   Figure 3 showing ABCB6 expression in mature erythrocytes

C.   Figure S4 detecting ABCB6 in secreted reticulocyte exosomes

D.   Figure 5 showing porphyrin synthesis and ABCB6 expression in K562 cells

A.   To prevent transmembrane proteins from embedding in the plasma membrane

B.   To add N-linked oligosaccharides to glycoproteins

C.   To break apart the plasma membrane

D.   To remove N-linked oligosaccharides from glycoproteins

A.   plasma membrane and hemoglobin

B.   nucleus, hemoglobin and mitochondria

C.   plasma membrane and nucleus

A.   TRUE

B.   FALSE

A.   They degrade the protein that is being targeted.

B.   They base pair with complementary sequences as a probe.

C.   They silence gene expression

D.   They increase gene expression.