Microbiology 020 - General Microbiology » Fall 2021 » Antimicrobial Treatment 1
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Question #1
Ceclor is an antibiotic that targets _______.
A.
folic acid synthesis
B.
protein synthesis
C.
DNA synthesis
D.
cell wall synthesis
Question #2
Cephalosporin antibiotics are derived from the natural products of _______.
A.
gram-variable bacilli
B.
fungi
C.
gram-positive cocci
D.
DNA viruses
Question #3
The symptoms of Ceclor allergy are due to the immediate quick destruction of a toxic infectious agent.
A.
TRUE
B.
FALSE
Question #4
This child has likely been on Ceclor _______.
A.
two times
B.
at least one time before this infection
C.
every time she has experienced an infection
D.
only this once
Question #5
Match the drug to the correct categoty based on your understanding of their cellular targets: Streptomycin
A.
Protein Synthesis
B.
DNA/RNA Synthesis
C.
Cell Wall
D.
Folic Acid Synthesis
Question #6
Match the drug to the correct categoty based on your understanding of their cellular targets: Tetracyclines
A.
Folic Acid Synthesis
B.
Protein Synthesis
C.
Cell Wall
D.
DNA/RNA Synthesis
Question #7
Match the drug to the correct categoty based on your understanding of their cellular targets: Erythromycin
A.
Cell Wall
B.
Protein Synthesis
C.
Folic Acid Synthesis
D.
DNA/RNA Synthesis
Question #8
Match the drug to the correct categoty based on your understanding of their cellular targets: Sulfonamides
A.
Folic Acid Synthesis
B.
Protein Synthesis
C.
DNA/RNA Synthesis
D.
Cell Wall
Question #9
Match the drug to the correct categoty based on your understanding of their cellular targets: Trimethoprim
A.
Protein Synthesis
B.
Folic Acid Synthesis
C.
Cell Wall
D.
DNA/RNA Synthesis
Question #10
Match the drug to the correct categoty based on your understanding of their cellular targets: Penicillins
A.
Cell Wall
B.
DNA/RNA Synthesis
C.
Folic Acid Synthesis
D.
Protein Synthesis
Question #11
Match the drug to the correct categoty based on your understanding of their cellular targets: Cephalosporins
A.
Protein Synthesis
B.
Folic Acid Synthesis
C.
DNA/RNA Synthesis
D.
Cell Wall
Question #12
Match the drug to the correct categoty based on your understanding of their cellular targets: Vancomycin
A.
Cell Wall
B.
Protein Synthesis
C.
DNA/RNA Synthesis
D.
Folic Acid Synthesis
Question #13
Match the drug to the correct categoty based on your understanding of their cellular targets: Ciprofloxacin
A.
Folic Acid Synthesis
B.
DNA/RNA Synthesis
C.
Protein Synthesis
D.
Cell Wall
Question #14
Match the drug to the correct categoty based on your understanding of their cellular targets: Rifampin
A.
DNA/RNA Synthesis
B.
Protein Synthesis
C.
Folic Acid Synthesis
D.
Cell Wall
Question #15
Which of the following drugs targets the cell wall and is responsible for the majority of allergic reactions to antimicrobial drugs?
A.
Penicillins
B.
Cephalosporins
C.
Streptomycin
D.
Sulfa drugs
Question #16
Antibiotics that target the cell wall interfere with the synthesis of _______.
A.
sterols
B.
enzymes
C.
peptidoglycan
D.
nucleic acids
Question #17
If the child was diagnosed with chickenpox as the mother had feared, what would the doctor likely have suggested for the child's Ceclor prescription?
A.
Finish the initial course prescribed for the bacterial ear infection
B.
Stop taking it immediately
C.
Increase the dosage and duration to combat the chickenpox infection
Question #18
How is the minimum inhibitory concentration (MIC) determined from a tube dilution test?
A.
It is the last tube that shows growth in the series
B.
It is the first tube that shows no growth in the series
C.
It is any tube in the series that does not show growth
Question #19
If Celcor has a toxic dose of 8 micrograms/milliliter, which would be the therapeutic index (in ratio form) of this drug?
A.
8/3.2
B.
6.4/8
C.
8/6.4
D.
3.2/8
Question #20
Based on your determined therapeutic index, how would the safety of Ceclor compare to an antibiotic with a therapeutic index (in ratio form) of 10/2?
A.
It would be much safer
B.
It would be more likely to result in serious side effects
C.
It would have the same level of safety
Question #21
Which of the following results from patient testing indicated a bacterial infection?
A.
Elevated red blood cell count
B.
Elevated white blood cell count
C.
Nitrates in the blood
D.
Protein in the blood
Question #22
Gentamicin is an antibiotic that inhibits ________.
A.
folic acid synthesis
B.
DNA synthesis
C.
protein synthesis
D.
cell wall synthesis
Question #23
Most urinary tract infections are caused by _______, such as Proteus mirabilis.
A.
gram-negative bacilli
B.
gram-positive cocci
C.
gram-variable bacilli
D.
gram-positive bacilli
Question #24
Antibiotics inhibiting peptidoglycan synthesis will negatively affect both bacterial and host cells.
A.
FALSE
B.
TRUE
Question #25
Which drug blocks the action of pyrophosphatase, thus inhibiting the transport of important molecules for cell wall synthesis across the bacterial membrane?
A.
Linezolid
B.
Trimethoprim
C.
Bacitracin
D.
Rifampin
Question #26
Which drug exerts its effect by weakening the cell wall until the bacterial cell is lysed?
A.
Rifampin
B.
Vancomycin
C.
Linezolid
D.
Bacitracin
Question #27
Which antibiotic inhibits the action of transpeptidase, resulting in weakening of the cell wall structure of bacteria?
A.
Tetracycline
B.
Polymyxin
C.
Penicillin
D.
Rifampin
Question #28
The patient is next treated with streptomycin. Is there a possibility she could still experience ringing in her ears?
A.
Yes, streptomycin is another aminoglycoside antibiotic.
B.
Yes, streptomycin is a cell wall inhibiting drug that also causes this effect.
C.
No, streptomycin is an RNA drug.
D.
No, streptomycin is a cell membrane inhibiting drug.
Question #29
Which of the following antibiotics are not involved in the blocking of cell wall synthesis and repair?
A.
Trimethoprim
B.
Vancomycin
C.
Penicillin
D.
Bacitracin
Question #30
Many of the antibiotics discussed in the animation target _______, such as pyrophosphatase and transpeptidase, involved in cell wall synthesis.
A.
lipids
B.
carbohydrates
C.
enzymes
D.
nucleic acids
Question #31
Match the antibiotic to its description to test your understanding of the different groups of penicillin antibiotics. Penicillin G and Penicillin V
A.
Added to penicillins to increase effectiveness against resistant bacteria
B.
Generally most effective against gram-positive bacteria
C.
Broad-spectrum drug, active against gram-positive bacteria and
D.
Effective against penicillinase-producing bacteria
Question #32
Match the antibiotic to its description to test your understanding of the different groups of penicillin antibiotics. Nafcilllin
A.
Broad-spectrum drug, active against gram-positive bacteria and
B.
Generally most effective against gram-positive bacteria
C.
Effective against penicillinase-producing bacteria
D.
Added to penicillins to increase effectiveness against resistant bacteria
Question #33
Match the antibiotic to its description to test your understanding of the different groups of penicillin antibiotics. Ampicillin
A.
Effective against penicillinase-producing bacteria
B.
Broad-spectrum drug, active against gram-positive bacteria and
C.
Generally most effective against gram-positive bacteria
D.
Added to penicillins to increase effectiveness against resistant bacteria
Question #34
Match the antibiotic to its description to test your understanding of the different groups of penicillin antibiotics. Clavulanic acid
A.
Added to penicillins to increase effectiveness against resistant bacteria
B.
Broad-spectrum drug, active against gram-positive bacteria and
C.
Effective against penicillinase-producing bacteria
D.
Generally most effective against gram-positive bacteria
Question #35
Viruses are able to multiply inside a nonliving cell.
A.
TRUE
B.
FALSE
Question #36
Individual viral particles have only one type of nucleic acid.
A.
TRUE
B.
FALSE
Question #37
Place the following steps of viral replication in their correct order: 1. release 2. adsorption 3. assembly 4. uncoating 5. synthesis
A.
2, 4, 5, 3, 1
B.
2, 5, 3, 2, 5
C.
5, 2, 1, 4, 3
D.
3, 2, 5, 4, 1
Question #38
Cells that lack compatible virus receptors are resistant to infection by that virus.
A.
FALSE
B.
TRUE
Question #39
What is the function of the reverse transcriptase enzyme?
A.
Synthesizes DNA from RNA
B.
Cleaves protein into capsomeres
C.
Synthesizes RNA from DNA
D.
Synthesizes protein
Question #40
During which stage of viral replication does amantadine exert its inhibitory effect?
A.
Viral assembly
B.
Synthesis of nucleic acids
C.
Penetration and uncoating
D.
Synthesis of capsid proteins
Question #41
When AZT is present, which enzyme is inhibited?
A.
Host RNA polymerase
B.
Viral protease
C.
Host DNA polymerase
D.
Viral reverse transcriptase
Question #42
Protease inhibitors ________.
A.
inhibit reverse transcriptase
B.
inhibit DNA polymerase
C.
inhibit processing of long polypeptide chains
D.
inhibit synthesis of interferons
Question #43
Of all the antiviral drugs, which is actually produced by the host?
A.
AZT
B.
Interferon
C.
Amantadine
D.
Foscarnet
Question #44
Which of the drugs inhibits DNA polymerase?
A.
Protease inhibitors
B.
Foscarnet
C.
Amantadine
D.
Interferon
Question #45
Which of the drugs is used to treat patients with HIV?
A.
Amantadine
B.
Interferon
C.
Foscarnet
D.
AZT
Question #46
Which step in the viral replication cycle would probably be the most efficient way to prevent viral infections?
A.
Adsorption
B.
Entry
C.
Synthesis
D.
Release
Question #47
What other way do we have to fight viral diseases?
A.
Over-the-counter drugs
B.
Vaccines
C.
Herbal remedies
D.
Antibiotics
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