Phar 642 - Principles of Drug Action » Spring 2022 » iRat 08
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Question #1
What part of the brain automatically alters respiration in response to input from chemoreceptors that monitor pH, oxygen, and carbon dioxide levels?
A.
Frontal cortex
B.
Medulla oblongata
C.
Cerebellum
D.
Hippocampus
Question #2
What decreases nasal secretions by directly inhibiting receptors on mucus glands?
A.
Pseudoephedrine
B.
Oxymetazoline
C.
Diphenhydramine
D.
Fluticasone
Question #3
What medication used in the treatment of cough is considered an antitussive?
A.
Acetaminophen
B.
N-acetylcysteine
C.
Codeine
D.
Guaifenesin
Question #4
What obstructive pulmonary disease is characterized by the destruction of alveoli?
A.
COPD
B.
Emphysema
C.
Chronic Bronchitis
D.
Asthma
Question #5
A patient was recently prescribed a long-acting β2-adrenergic agonist to control the symptoms of asthma. What drug was the patient most likely prescribed?
A.
Ipratropium
B.
Albuterol
C.
Tiotropium
D.
Salmeterol
Question #6
What bronchodilator is most likely to have adverse effects due to being metabolized by cytochrome P450?
A.
Albuterol
B.
Theophylline
C.
Fluticasone
D.
Prednisone
Question #7
A patient was recently prescribed a drug that decreased activity of leukotrienes and prostaglandins in his lungs. What drug was the patient most likely prescribed?
A.
Montelukast
B.
Cromolyn sodium
C.
Fluticasone
D.
Zileuton
Question #8
A 29-year-old female patient that has been taking lithium developed symptoms of thyroid dysfunction caused by inhibition of thyroid hormone release. What would you expect to see in this patient’s lab results?
A.
High TSH, high free thyroxine
B.
Low TSH, high free thyroxine
C.
High TSH, low free thyroxine
D.
Low TSH, low free thyroxine
Question #9
A 29-year-old male patient was prescribed desmopressin, a drug that mimics antidiuretic hormone, by his physician. What condition was this drug most likely prescribed to manage?
A.
Diabetes mellitus
B.
Diabetes insipidus
C.
Syndrome of inappropriate antidiuretic hormone secretion (SIADH)
D.
Hyperkalemia
Question #10
A 35-year-old female patient was prescribed a drug to manage symptoms of hypothyroidism. What drug was most likely prescribed?
A.
Methimazole
B.
Radioactive Iodine
C.
Levothyroxine
D.
Thyrotropin
Question #11
A 45-year-old male patient was diagnosed with secondary adrenal insufficiency following a traffic accident that resulted in damage to his pituitary gland. What pharmacological option would be most helpful for this patient?
A.
A glucocorticoid antagonist
B.
An ACTH inhibitor
C.
A mineralocorticoid agonist
D.
A corticosteroid
Question #12
A 45-year-old male patient with chronic kidney disease was diagnosed with secondary hyperparathyroidism, a disease involving increased parathyroid hormone levels due to a cause not involving the parathyroid gland. What mechanism most likely caused the patient to develop this complication?
A.
High levels of free serum magnesium
B.
Low levels of free serum phosphate
C.
Low levels of free serum calcium
D.
High levels of free serum sodium
Question #13
A 55-year-old female patient was prescribed metformin to help manage type 2 diabetes mellitus. What mechanism most likely contributes to the beneficial effect of this drug for this patient?
A.
Phosphorylation of GLUT4 transport proteins
B.
Activation of glucagon-like peptide-1 receptors
C.
Activation of nuclear PPAR-ƒ× receptors
D.
Antagonism of dipeptidyl peptidase 4
Question #14
A 45-year-old female patient was prescribed a drug as part of her treatment regimen for type 2 diabetes mellitus that inhibits ATP-sensitive potassium channels in -cells of the pancreas. What type of drug was she most likely prescribed?
A.
Biguanide
B.
Thiazolidinedione
C.
á-Glucosidase inhibitors
D.
Sulfonylurea
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