Physiology 001 - Introduction to Human Physiology » Fall 2022 » Laboratory Midterm Exam
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Question #1
The driving force for diffusion is ________________.
A.
The membrane transport protein
B.
ATP
C.
The kinetic energy of the molecules in motion
D.
The plasma membrane
Question #2
In diffusion, molecules move____________.
A.
From high concentration to low concentration
B.
From either high or low concentration
C.
From low concentration to high concentration
D.
Against a concentration gradient
Question #3
In your diffusion lab exercise, the dialysis membranes had a molecular weight cutoff (MWCO) which is related to pore size. Which of the following dialysis membranes has the largest pore size?
A.
20 MWCO
B.
100 MWCO
C.
200 MWCO
D.
50 MWCO
Question #4
If the dialysis membrane is permeable to sodium chloride, then an increase in the concentration of sodium chloride should _________________.
A.
Increase the rate of diffusion
B.
Decrease the rate of diffusion
C.
Make no change to the rate of diffusion
Question #5
Larger molecules have a ______________ rate of diffusion.
A.
Slower
B.
Faster
Question #6
If the MWCO of a dialysis membrane is 50, and the molecular weight of glucose is 25 grams per mole; the molecular weight of albumin is 75 grams per mole; and the molecular weight of urea is 150 grams per mole; which molecule(s) will be able to pass through the membrane?
A.
Albumin
B.
Glucose and Urea
C.
Urea
D.
Albumin and Urea
E.
Glucose and Albumin
F.
Glucose
Question #7
_________________is reached when diffusion stops.
A.
Equilibrium
B.
Maturation
C.
Concentration
D.
Saturation
Question #8
Molecules need a carrier protein to help move them across a membrane because ________________.
A.
They are lipid insoluble
B.
They are lipid insoluble or too large
C.
They are lipid soluble
D.
They are too large
Question #9
Which of the following is true of facilitated diffusion?
A.
Movement is passive and down a concentration gradient
B.
Movement is active and against a concentration gradient
C.
Movement is passive and against a concentration gradient
D.
Movement is active and down a concentration gradient
Question #10
Which of the following would not affect the rate of facilitated diffusion?
A.
Steepness or size of the concentration gradient
B.
The number of membrane carriers
C.
The amount of intracellular ATP
D.
The concentration of solutes
Question #11
What variable(s) increase the rate of facilitated diffusion of glucose?
A.
Adding sodium chloride
B.
Increasing the concentration of glucose and increasing the number of glucose membrane carrier proteins
C.
Increasing the number of glucose membrane carrier proteins
D.
Increasing the concentration of glucose
Question #12
For facilitated diffusion, increasing the concentration of glucose on one side of the membrane is the same as_____________________.
A.
Adding ATP
B.
Making the concentration gradient steeper
C.
Making the concentration gradient flatter
D.
Changing the direction of diffusion
Question #13
When all of the membrane carriers are engaged, or busy, we say they are _______________________.
A.
Inhibited
B.
Selected
C.
Satiated
D.
Saturated
Question #14
Which of the following is true of osmosis?
A.
It is a type of diffusion
B.
Movement is against the concentration gradient of water
C.
It refers to the movement of solutes
D.
It requires energy
Question #15
Which of the following occurs when a hypertonic solution is added to cells?
A.
The cells shrink
B.
The cells burst
C.
Water enters the cells
D.
The cells swell
Question #16
The variable that affects osmotic pressure is _______________.
A.
The pore size of the membrane proteins
B.
The concentration of impermeable solutes
C.
The concentration of permeable solutes
D.
The rate of diffusion
Question #17
The net movement of water would be into the cell in a __________________.
A.
Isotonic solution
B.
Hypotonic solution
C.
Hypertonic solution
Question #18
Water diffuses ________________.
A.
Toward solutes
B.
Away from solutes
C.
By utilizing ATP
D.
Against its concentration gradient
Question #19
Filtration is a process that _____________________.
A.
Requires ATP
B.
Is active and requires ATP
C.
Is passive
D.
Is active
Question #20
Filtration is dependent upon a _________________________.
A.
Hydrostatic pressure gradient
B.
Concentration gradient
C.
Kinetic energy gradient
D.
Osmotic pressure gradient
Question #21
An important place that filtration takes place in the body is in __________________.
A.
The muscles
B.
The ovaries
C.
The Kidneys
D.
The skin
Question #22
After filtration, the substance that pass through the filter is called the filtrate. This filtrate includes both solvent and solutes.
A.
True
B.
False
Question #23
An increase in blood pressure would probably initially _____________filtration in the kidneys.
A.
Stop
B.
Increase the rate of
C.
Decrease the rate of
D.
Block
Question #24
The movement of sodium and potassium maintained by the Na+/K+ pump ___________________.
A.
Requires energy
B.
Is down a concentration gradient
C.
Requires energy and is against the concentration gradient
D.
Is against the concentration gradient
E.
Requires diffusion
Question #25
The Sodium-Potassium Pump is classified as a(n) __________________________.
A.
Uniporter
B.
Antiporter
C.
Symporter
D.
Isoporter
Question #26
The sodium-potassium pump moves _________ sodium ions and ___________ potassium ions simultaneously.
A.
3 ; 3
B.
2 ; 2
C.
2 ; 3
D.
3 ; 2
Question #27
Solutes that require active transport for movement might be too large to pass or might be _____________.
A.
Lipid soluble
B.
Too small to pass
C.
Able to move down a concentration gradient
D.
Lipid insoluble
Question #28
What is the approximate concentration of K+ inside a typical cell (intracellular concentration)?
A.
0 mM
B.
5 mM
C.
15 mM
D.
150 mM
Question #29
What is the approximate concentration of K+ outside of a cell (extracellular concentration)?
A.
5 mM
B.
0 mM
C.
150 mM
D.
15 mM
Question #30
What is the approximate concentration of Na+ inside a cell?
A.
150 mM
B.
15 mM
C.
5 mM
D.
0 mM
Question #31
What is the approximate concentration of Na+ outside a cell?
A.
5 mM
B.
150 mM
C.
0 mM
D.
15 mM
Question #32
Voltage-gated Na+ channels are membrane channels that open ____________________.
A.
When the membrane is at the resting membrane potential
B.
When the membrane depolarizes
C.
When lidocaine is applied to the membrane
D.
When tetrodotoxin (TTX) is applied to the membrane
Question #33
When open, Na+ channels allow _______________________.
A.
K+ ions to diffuse out of the cell
B.
K+ ions to diffuse into the cell
C.
Na+ ions to diffuse out of the cell
D.
Na+ ions to diffuse into the cell
Question #34
Lidocaine increases the likelihood of an action potential occuring.
A.
False
B.
True
Question #35
Puffer fish must be prepared carefully and properly before they can be eaten. Eating puffer fish can cause numbness of the lips, probably because _____________________.
A.
There are no neurons in the lips
B.
Puffer fish do not taste good
C.
Action potentials from sensory neurons in the lips are blocked.
D.
Tetrodotoxin (TTX) alters the resting membrane potential of all neurons in the lips
Question #36
What is meant by Na+ channel inactivation?
A.
The Na+ channel opens when the membrane reaches threshold
B.
The Na+ channel no longer allows Na+ ions to pass through it
C.
The Na+ channel allows K+ ions to diffuse into the cell
D.
The Na+ channel allows Na+ ions to diffuse out of the cell
Question #37
A.
True
B.
False
Question #38
One reason why it is harder to generate a second action potential soon after the first action potential because some of the voltage-gated Na+ channels are inactivated.
A.
False
B.
True
Question #39
An action potential can be propagated along an axon because there are __________channels in the membrane.
A.
Voltage-gated
B.
Odor-sensitive
C.
Pressure-sensitive
D.
Temperature-sensitive
Question #40
The units of conduction velocity are ______________.
A.
Volts
B.
meters per second
C.
Seconds
D.
Millivolts
Question #41
Which of the following will affect axonal conduction velocity?
A.
The amount of myelination
B.
Neither the diameter of the axon nor the amount of myelination
C.
Both the diameter of the axon and the amount of myelination
D.
The diameter of the axon
Question #42
Which of the following describes an A type fiber/axon?
A.
Large diameter and heavily myelinated
B.
Medium diameter and lightly myelinated
C.
Small diameter and unmyelinated
Question #43
Which of the following describes a C type fiber/axon?
A.
Small diameter and unmyelinated
B.
Medium diameter and lightly myelinated
C.
Large diameter and heavily myelinated
Question #44
Action potential conduction velocity is fastest in which of the following fibers?
A.
B type fibers
B.
A type fibers
C.
C type fibers
D.
The conduction velocity is the same for all three types of fibers
Question #45
Action potential conduction velocity is slowest in which of the following fibers?
A.
The conduction velocity is the same for all three fibers
B.
Type C fibers
C.
Type A fibers
D.
Type B fibers
Question #46
A.
Neither touch nor pain would be perceived
B.
Your toe touching something
C.
Both touch and pain would be perceived at the same time
D.
Pain
Question #47
The end of the axon where it contacts a target is called the __________________.
A.
myelin sheath
B.
Axon terminal
C.
Nucleus
D.
Cell body
Question #48
Neurotransmitter is released into the synaptic gap by _____________________.
A.
Voltage-gated neurotransmitter channels
B.
The postsynaptic membrane of the target cell
C.
Exocytosis
D.
Muscle contraction
Question #49
Exocytosis of neurotransmitter from the axon terminal is triggered by an increase in the intracellular concentration of _________________.
A.
K+
B.
Na+
C.
Both Na+ and K+
D.
Ca2+
Question #50
At the target tissue, neurotransmitter binds to receptor proteins on the postsynaptic membrane.
A.
True
B.
False
Question #51
How is the neurotransmitter stored in the axon terminal before it is secreted?
A.
Bound to Ca2+ channels
B.
Neurotransmitter moves freely throughout the axon terminal
C.
Bound to mitochondria
D.
Contained in synaptic vessicles
Question #52
Are neurotransmitter molecules released one at a time or in packets?
A.
In packets
B.
One at a time
Question #53
Skeletal muscles are connected to bones by _________________.
A.
Tendons
B.
Joints
C.
Motor axons
D.
Ligaments
Question #54
Skeletal muscles are composed of hundreds to thousands of individual cells called _______________.
A.
Myofilaments
B.
Fibers
C.
Sarcomeres
D.
Myofibrils
Question #55
The term motor unit refers to _______________.
A.
One motor neuron and all of the skeletal muscle fibers it innervates
B.
All of the activated muscle fibers within one skeletal muscle
C.
All of the motor neurons that innervate on skeletal muscle
D.
One motor neuron that innervates several skeletal muscles
Question #56
The motor neuron and the muscle fiber intersect at what is called the _________________.
A.
Inhibitory synapse
B.
Pre-synaptic nerve terminal
C.
Excitatory synaspe
D.
Neuromuscular junction
Question #57
An action potential in a motor neuron triggers the release of which neurotransmitter (to activate the sarcolemma)?
A.
Glutamate
B.
Norepinephrine
C.
Acetylcholine
D.
Glycine
Question #58
The term skeletal muscle fiber refers to an individual ____________________.
A.
Skeletal muscle cell
B.
Sarcomere
C.
Skeletal muscle, such as the biceps or the triceps
D.
Myosin fiber
Question #59
The graded depolarization in the skeletal muscle fiber that is elicited in response to one action potential from the motor neuron is called a(n) ______________________.
A.
EPP (end-plate potential)
B.
EPSP (excitatory postsynaptic potential)
C.
IPSP (inhibitory postsynaptic potential)
D.
Threshold potential
Question #60
Which of the following is not a phase of a skeletal muscle twitch?
A.
Relaxation
B.
Hyperpolarization
C.
Latent period
D.
Contraction
Question #61
A skeletal muscle twitch is _________________________.
A.
One contractile response to a train of action potentials
B.
One contractile response to a single action potential
C.
Multiple contractile responses to a single action potential
D.
Multiple contractile responses to a train of action potentials
Question #62
Which of the following correctly matches the twitch phase with its definition?
A.
The contraction phase: the time between an action potential in a muscle cell and the start of muscle tension
B.
The relaxation phase: the time between electrical stimuli
C.
The contraction phase: the time between the end of the latent period and peak muscle tension
D.
The latent period: the time from peak tension until the end of the muscle contraction
Question #63
Skeletal muscle fibers are innervated (stimulated) by ____________________.
A.
Interneurons
B.
Symphathetic neurons
C.
Motor neurons
D.
Parasympathetic neurons
Question #64
In a resting skeletal muscle, calcium is stored in the __________________.
A.
Cytosol
B.
Myofibril
C.
Sarcoplasmic reticulum
D.
Sarcomere
Question #65
Motor unit recruitment refers to a(n) _____________________.
A.
Increase in the number of active muscle fibers to decrease the work a muscle must perform
B.
Decrease in the number of active muscle fibers to increase the simplicity of the force development in a muscle
C.
Decrease in the number of active muscle fibers to decrease the force developed in a muscle
D.
Increase in the number of active muscle fibers to increase the force developed in a muscle
Question #66
Active tension (or force) in a skeletal muscle fiber results from _____________________.
A.
Detachment of the tendons from the bones in the body
B.
Moving the muscle on its support stand
C.
Activation of cross bridge cycling because of increased intracellular calcium levels
D.
Stretching the muscle before applying the stimulus voltage
Question #67
The ______________ is the minimal stimulus needed to cause a depolarization of the muscle plasma membrane (sarcolemma).
A.
Latent voltage
B.
Motor unit voltage
C.
Threshold voltage
D.
Maximal voltage
Question #68
By definition, the ___________ is the amount of stimulus required to successfully recruit ALL the muscle fibers into developing active force.
A.
Maximal voltage
B.
Motor unit voltage
C.
Contractile stimulus voltage
D.
Latent voltage
Question #69
When a skeletal muscle is repetitively stimulated, twitches can overlap each other an result in a stronger muscle contraction than a stand-alone twitch. This phenomenon is known as ____________________.
A.
The latent period
B.
Fatigue
C.
Wave summation
D.
Skeletal muscle tone (or tonus)
Question #70
Wave summation is achieved by allowing the muscle to completely relax between stimuli.
A.
True
B.
False
Question #71
Wave summation does not increase the force produced in a muscle.
A.
False
B.
True
Question #72
When a muscle receives a stimulus frequency that causes non-overlapping twitches to follow each other closely in time such that the peak tension of each twitch rises in a stepwise fashion, the result is known as _________.
A.
Treppe
B.
Frappe
C.
Motor unit recruitment
D.
Wave summation
Question #73
The rate of stimulus frequency (delivery) is greater during a state of unfused tetanus than in a state of fused (complete) tetanus.
A.
True
B.
False
Question #74
When the stimulus frequency reaches a value beyond which no further increases in force are generated by the muscle, the muscle has reached its maximal tetanic tension.
A.
False
B.
True
Question #75
The term tetanus refers to sustained muscle tension due to very frequent stimuli.
A.
True
B.
False
Question #76
Changes in the stimulus intensity of skeletal muscle will change the duration of the latent period.
A.
False
B.
True
Question #77
Treppe is also known as the staircase effect.
A.
True
B.
False
Question #78
Wave summation occurs in the body when a sensory-neuron that innervates a skeletal muscle fiber increases the stimulation frequency.
A.
False
B.
True
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