Nursing 1141- Pharmacology » Fall 2022 » Mastery EAQ Ch. 26

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Question #1
A patient has overdosed on warfarin. Which substance will the nurse administer to reverse the effect of warfarin?
A.   Aspirin
B.   Calcium
C.   Vitamin K
D.   Potassium
Question #2
A patient who is on enoxaparin therapy has hematuria, melena, petechiae, and bleeding from the gums. Which treatment strategy will be beneficial for the patient?
A.   Administering vitamin K1
B.   Administering protamine sulfate
C.   Increasing the dose of enoxaparin
D.   Infusing 50 mL of warfarin sodium
Question #3
A patient who was admitted with deep vein thrombophlebitis is complaining of difficulty breathing and chest pain. Which is the most likely cause of these symptoms?
A.   Embolus to the lungs
B.   Anxiety
C.   Medication reaction
D.   Fatigue from walking with pain
Question #4
Cilostazol belongs to which drug class?
A.   Antiplatelet
B.   Thrombolytic
C.   Antifibrinolytic
D.   Anticoagulant
Question #5
The nurse is teaching a patient about therapy with anticoagulants. Which is essential information to include in the teaching plan?
A.   Anticoagulants alter platelet function.
B.   Anticoagulants prevent clots from forming.
C.   Anticoagulants dissolve clots.
D.   Anticoagulants interfere with drug metabolism.
Question #6
Which subclass of anticoagulants may cause the adverse effect of purple toes?
A.   Heparins
B.   Warfarin
C.   Selective factor Xa inhibitors
D.   Direct thrombin inhibitors
Question #7
Which anticoagulant can be given orally?
A.   Argatroban
B.   Dabigatran
C.   Fondaparinux
D.   Enoxaparin
Question #8
Which antiplatelet drug works by inhibiting the cyclooxygenase in the platelet irreversibly so that the platelet cannot regenerate this enzyme, thereby preventing clot formation?
A.   Aspirin
B.   Cilostazol
C.   Dipyridamole
D.   Pentoxifylline
Question #9
Which condition is an indication for thrombolytic therapy?
A.   Coronary artery disease
B.   Heart failure
C.   Acute myocardial infarction
D.   Cardiomyopathy
Question #10
Which class of drugs is also known as hemostatic drugs?
A.   Thrombolytic
B.   Antifibrinolytic
C.   Antiplatelet
D.   Anticoagulant
Question #11
Which antifibrinolytic agent is used for surgical and postoperative hemostasis?
A.   Alteplase
B.   Desmopressin
C.   Tranexamic acid
D.   Aminocaproic acid
Question #12
A nurse understands that warfarin works by affecting which substance?
A.   Vitamin K
B.   Antithrombin III
C.   Thrombin
D.   Factor Xa
Question #13
A patient with deep vein thrombosis is receiving fondaparinux therapy. After reviewing the patient’s laboratory reports, the nurse believes that discontinuing the therapy will be beneficial for the patient. Which finding supports the nurse’s suspicion?
A.   Creatinine clearance value of 40 mL/min
B.   Hemoglobin level of 16.5 g/dL
C.   Platelet count of 75,000 cell/μL
D.   Fasting blood glucose level of 95 mg/dL
Question #14
A patient is receiving an intravenous heparin drip. Which laboratory value requires immediate action by the nurse?
A.   Platelet count of 150,000 mm3
B.   Blood urea nitrogen (BUN) level of 12 mg/dL
C.   Activated partial thromboplastin time (aPTT) of 120 seconds
D.   International normalized ratio (INR) of 1.0
Question #15
The patient has been placed on aspirin as an antiplatelet drug. Which is a side effect of aspirin therapy?
A.   Chest pain
B.   Edema
C.   Itching
D.   Nausea
Question #16
The patient is being treated with dabigatran and opens a new bottle of the medication on July 1. The nurse will instruct the patient to discard any unused medication by which date?
A.   July 31
B.   August 29
C.   October 1
D.   September 15
Question #17
A patient who is receiving heparin therapy has bruises covering the abdomen as well as red-colored urine. Which assessment does the nurse need to address?
A.   Urine culture
B.   Ingestion of acetaminophen
C.   Over-the-counter medications
D.   Platelet level
Question #18
The nurse is preparing to administer an anticoagulant to a patient. Which medication and route of administration is in error?
A.   Enoxaparin intramuscularly
B.   Dabigatran orally
C.   Warfarin orally
D.   Heparin subcutaneously
Question #19
Which condition is a contraindication to therapy with an antiplatelet drug?
A.   Vitamin K deficiency
B.   Peripheral vascular disease
C.   Acute unstable angina
D.   Transient ischemic attack
Question #20
A patient is diagnosed with hemophilia. Which medication therapy is essential?
A.   Recombinant factors
B.   Vitamin K daily
C.   Aspirin daily (i.e., 81 mg)
D.   Warfarin daily
Question #21
A patient who has been taking warfarin is admitted with coffee-ground emesis. Which medication would the nurse anticipate being prescribed for this patient?
A.   Vitamin K
B.   Protamine sulfate
C.   Calcium gluconate
D.   Vitamin E
Question #22
A patient is receiving warfarin for a chronic condition. Which patient statement requires immediate action by the nurse?
A.   "I will increase dark green leafy vegetables in my diet."
B.   "I will take my medication at the same time each day."
C.   "I will contact my health care provider if I develop excessive bruising."
D.   "I will avoid contact sports."
Question #23
A nurse is preparing to administer enoxaparin sodium to a patient for prevention of deep vein thrombosis. Which nursing intervention is essential?
A.   Utilize the Z-track method to inject the medication.
B.   Administer the medication into subcutaneous tissue of the abdomen.
C.   Rub the administration site after injecting.
D.   Draw up the medication in a syringe with a 22-gauge, 1.5-inch needle.
Question #24
The patient asks the nurse to explain the difference between dalteparin and regular heparin. Which response by the nurse is accurate?
A.   "Dalteparin is a low-molecular-weight heparin that is more predictable in its effect and has a lower risk of bleeding."
B.   "There is no real difference; dalteparin is interchangeable with regular heparin."
C.   "The only difference is that regular heparin dosing is based on the patient’s weight."
D.   "You should ask your doctor why dalteparin was ordered instead of regular heparin."
Question #25
The nurse confirms that a patient has understood discharge teaching regarding warfarin based on which statement by the patient?
A.   "I should use a soft toothbrush for dental hygiene."
B.   "I will double my dose if I forget to take it the day before."
C.   "I should keep taking ibuprofen for my arthritis."
D.   "I should decrease the dose if I start bruising easily."
Question #26
The nurse is teaching a patient who is receiving aminocaproic acid the measures to prevent adverse effects. Which statement made by the patient indicates the need for further teaching?
A.   "I should follow a low-cholesterol diet during the therapy."
B.   "I should not use any acetaminophen during the therapy."
C.   "I should take oral contraceptives during the therapy."
D.   "I should refrain from eating broccoli during the therapy."
Question #27
The nurse is administering tenecteplase (TNKase) therapy to a patient experiencing an acute myocardial infarction. Which outcome is expected from this therapy?
A.   Dissolution of the clot that caused the heart attack
B.   Prevention of new clots from forming
C.   Reversal of damage from the infarction
D.   A quick decrease in pain
Question #28
A patient receiving warfarin has an international normalized ratio (INR) of 6. Which action would the nurse take?
A.   Administer vitamin K1 (phytonadione) IV.
B.   Stop the intravenous (IV) drip.
C.   Wait for the INR to decrease.
D.   Administer protamine sulfate IV.
Question #29
The patient is being treated with a continuous intravenous infusion of heparin. Which action is the nurse’s highest priority?
A.   Monitor the patient’s laboratory values correctly.
B.   Ensure that a loading dose was initially administered when beginning
C.   Teach the patient about dietary restrictions while on the medication.
D.   Have protamine sulfate readily available at all times.
Question #30
A patient with atrial fibrillation is admitted to the emergency unit for symptoms of warfarin toxicity. The primary health care provider instructs the nurse to administer 6 mg of vitamin K to the patient. Which medication would be included in the patient’s prescription to provide safe and effective treatment?
A.   Enoxaparin
B.   Ketoconazole
C.   Amiodarone
D.   Furosemide
Question #31
Which instruction will the nurse provide to the patient regarding storing dabigatran for home use?
A.   "Refrigerate and keep away from direct sunlight."
B.   "Store the drug with the desiccant-drying agent in the packing cap."
C.   "Remove from the original package and place in aluminum foil."
D.   "Discard the drug within 21 days of opening the original container."
Question #32
The patient is receiving warfarin therapy, and the nurse finds the international normalized ratio (INR) to be 4.0. Which interpretation of the INR finding is correct?
A.   Outside the expected target therapeutic level of anticoagulation; it is too low
B.   The prothrombin time and activated partial thromboplastin time (aPTT) value are needed to interpret the finding.
C.   Within the expected target therapeutic level of anticoagulation
D.   Outside the expected target therapeutic level of anticoagulation; it is too high
Question #33
The nurse is reviewing laboratory data before initiating a patient’s heparin infusion. Which finding requires immediate action?
A.   Potassium level of 3.5 mEq/L
B.   Platelet count of 95,000/mm3
C.   Activated partial thromboplastin time (aPTT) of 37 seconds
D.   International normalized ratio (INR) of 1
Question #34
Which condition is a contraindication for dabigatran?
A.   Chronic obstructive pulmonary disease, Atrial fibrillation
B.   History of myocardial infarction, Chronic obstructive pulmonary disease
C.   Peptic ulcer disease, Chronic kidney disease
D.   Atrial fibrillation, History of myocardial infarction
Question #35
After reviewing the laboratory reports of a patient who was prescribed long-term heparin therapy, the nurse is asked to administer argatroban. Which laboratory result indicates the need for this medication?
A.   Leukocyte count: 3000 cells/mm3
B.   Hemoglobin level: 11 g/dL
C.   Platelet count: 100,000/mm3
D.   Prothrombin time: 13 sec
Question #36
A patient who is undergoing treatment with heparin therapy has an activated partial thromboplastin time (aPTT) level of 98 seconds. Which interpretation of this level is correct?
A.   Within the expected target therapeutic level of anticoagulation
B.   Outside the expected target therapeutic level of anticoagulation; it is too low
C.   Cannot be interpreted without knowing the prothrombin time and international normalized ratio
D.   Outside the expected target therapeutic level of anticoagulation; it is too high
Question #37
A patient has been receiving intravenous heparin. The nurse notes that today’s activated partial thromboplastin time (aPTT) result is elevated. Which action would the nurse take?
A.   Stop the medication.
B.   Monitor the patient and check the therapeutic range.
C.   Increase the dose of heparin.
D.   Notify the health care provider immediately.
Question #38
Alteplase therapy is indicated for a patient with which condition?
A.   Local thrombosis from a peripheral intravenous line
B.   Severe chest pain for the past 2 hours
C.   Peptic ulcer disease
D.   Gastrointestinal bleed
Question #39
The nurse is caring for a patient who is being treated with warfarin. The patient has just been administered cimetidine. Which action would the nurse take?
A.   Monitor the patient for increased action of the anticoagulant.
B.   Instruct the patient to notify the nurse if he or she begins to experience discomfort.
C.   Continue to administer cimetidine with each dose of warfarin.
D.   Monitor the patient for decreased action of the anticoagulant.
Question #40
The nurse is caring for a patient who is scheduled to begin warfarin treatment and is currently being treated with amiodarone. Considering this information, the nurse anticipates that which change will be made to the medication regimen?
A.   The dosage of the amiodarone will be decreased by half.
B.   The dosage of the amiodarone will be increased by half.
C.   The dosage of the warfarin will be increased by half.
D.   The dosage of the warfarin will be decreased by half.
Question #41
A patient is prescribed dabigatran to treat atrial fibrillation. On a follow-up visit, the medication dose is reduced by half. Which assessment finding supports the change in the prescribed dose?
A.   Diagnosis of diabetes mellitus
B.   Platelet count of 80,000/mm3
C.   Loss of 10 pounds
D.   Creatinine clearance of 25 mL/min
Question #42
Which patient statement indicates a need for additional teaching about the safe use of dabigatran?
A.   "I will store the bottle in a dry place."
B.   "I will take the medication with food."
C.   "I will place the pills in an organizer for easy use."
D.   "I will use the medication within 60 days after it is opened."
Question #43
The nurse is caring for a patient who is prescribed long-term aspirin therapy to prevent a stroke. Which parameters would the nurse assess as a result of this prescription?
A.   Activated partial thromboplastin time (aPTT), Blood pressure, Heart rate
B.   Heart rate, Hemoglobin, Blood pressure
C.   Hemoglobin, Platelet count, Activated partial thromboplastin time (aPTT)
D.   Platelet count, Heart rate, Blood pressure
Question #44
In a patient receiving warfarin therapy, the addition of which medication would require the dose of warfarin to be increased?
A.   Barbiturate
B.   Cholestyramine
C.   Cimetidine
D.   Carbamazepine
Question #45
A patient is experiencing chest pain, dyspnea, hemoptysis, and hypotension. The patient’s arterial blood gas analysis indicates a decreased level of oxygen. Which medication prescription would the nurse expect for the patient based on the current assessment data?
A.   Aminocaproic acid
B.   Phytonadione
C.   Alteplase
D.   Tranexamic acid
Question #46
  
A.   "I never sit with my legs crossed at the knees."
B.   "I’ve been on prolonged bed rest."
C.   "I get up and walk around at least once an hour."
D.   "I avoid tight-fitting stockings or leggings."
Question #47
After talking with a patient who is receiving warfarin sodium therapy, the nurse believes that the patient is at increased risk for bleeding. Which statement made by the patient supports the nurse’s conclusion?
A.   "I refrain from drinking coffee and citrus fruit juices daily."
B.   "I do not take aspirin for pain relief."
C.   "I eat 1 cup of green leafy vegetables daily."
D.   "I take ginkgo supplements for memory enhancement."
Question #48
A registered nurse is teaching a student nurse about safe and effective administration of heparin. Which action by the student nurse is appropriate?
A.   Massaging the site after the injection
B.   Administering the medication intramuscularly in the vastus lateralis
C.   Checking if the patient’s prescription contains enoxaparin
D.   Administering the medication when convenient
Question #49
Which nursing intervention is essential for a patient receiving alteplase?
A.   Administer prescribed vitamin K if bruising is observed.
B.   Monitor liver enzymes.
C.   Assess for dysrhythmias.
D.   Stop the medication if the systolic blood pressure drops below 110 mm Hg.
Question #50
The nurse assesses the patient’s prothrombin time (PT) to determine the effectiveness of anticoagulant therapy and notes that it is 32 seconds. Which interpretation of this PT value is correct?
A.   Significantly elevated
B.   Significantly decreased
C.   Inadequate to evaluate treatment
D.   Within normal limits
Question #51
The nurse assesses the patient’s activated partial thromboplastin time (aPTT) to determine the effectiveness of the heparin regimen and notes that it is 35 seconds. Which interpretation of this aPTT is correct?
A.   Too high
B.   Within normal limits
C.   Too low
D.   Inadequate to evaluate treatment
Question #52
The nurse is screening a patient for candidacy for treatment with fondaparinux. The nurse reviews the patient’s laboratory test results and finds a creatinine clearance of 20 mL/min and a body weight of 48 kg. Which interpretation of these findings is correct?
A.   Not a candidate for fondaparinux based on both an insufficient creatinine clearance and an inadequate body weight
B.   Not a candidate for fondaparinux based on an insufficient creatinine clearance
C.   Is a candidate for fondaparinux based on a sufficient creatinine clearance and adequate body weight
D.   Is a candidate for fondaparinux based on sufficient creatinine clearance and after body weight attains an adequate level
Question #53
The nurse is caring for a patient who is being treated with fondaparinux and notes a platelet count of 80,000/mm3. Based on this information, the nurse anticipates which change to the medication regimen?
A.   The dose will be decreased.
B.   The medication will be stopped.
C.   The dose will be increased.
D.   The dose will be unchanged.

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