EOH 353 - Global Perspective of Environmental Health » Spring 2020 » Chapter 3 Quiz

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Question #1
The existence of a dose-response relationship may be used to establish which of the following kinds of information?
A.   Causal association between a toxin and biological effects
B.   Rate of accumulation of harmful effects
C.   Minimum dosages needed to produce a biological effect
D.   Both causal association between a toxin and biological effects and minimum dosages needed to produce a biological effect
E.   All of these are correct.
Question #2
Of the following routes of exposure, which one has the most rapid effect?
A.   Intravenous
B.   Inhalation
C.   Intramuscular
D.   Dermal
E.   Ingestion
Question #3
The poisonous substance in Amanita phalloides (“death cap” mushroom) is an example of a(n):
A.   poison caused by bacterial activity.
B.   anthropogenic form of poison
C.   toxicant.
D.   toxin.
E.   None of these is correct.
Question #4
Subacute exposures are those that last for:
A.   less than 24 hours and occur once.
B.   1 to 3 months.
C.   1 month or less.
D.   less than 24 hours and occur more than once.
E.   more than 3 months.
Question #5
One of the founders of toxicology was:
A.   Theophrastus.
B.   Socrates.
C.   Da Vinci.
D.   Claudius.
E.   Paracelsus.
Question #6
The concentration and toxicity of a chemical in the body are affected by:
A.   route of entry into the body.
B.   All of these are correct.
C.   duration of exposure.
D.   individual sensitivity.
E.   received dose of the chemical.
Question #7
An internal dose refers to the:
A.   amount of a substance that is available to the internal organs of the body.
B.   portion of a substance that becomes internalized in the body.
C.   None of these is correct.
D.   quantity of a substance that is administered
E.   dose acquired by contact with contaminated environmental sources.
Question #8
Which of the following is an example of in vitro testing for toxicology?
A.   Experiments with volunteers who have had unintentional exposures
B.   Experiments with cells derived from human sources
C.   Studies of animals exposed to toxins
D.   Experiments with normal volunteers
E.   Dose-response assessments in human populations
Question #9
When highly controlled and standardized conditions are desired, human subjects are used in toxicologic testing.
A.   TRUE
B.   FALSE
Question #10
Which term indicates that the combined effect of exposures to two or more chemicals that is greater than the sum of their individual effects?
A.   Antagonistic
B.   Synergistic
C.   Additive
D.   Coalitive
Question #11
All of the following statements about thalidomide are true, except:
A.   it was used to treat morning sickness during pregnancy.
B.   it was a potent teratogen.
C.   it was associated with heart problems among adults.
D.   it was developed before the advent of rigorous clinical trials.

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