EOH 353 - Global Perspective of Environmental Health » Spring 2020 » Chapter 3 Quiz

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Question #1
The existence of a dose-response relationship may be used to establish which of the following kinds of information?
A.   Rate of accumulation of harmful effects
B.   Minimum dosages needed to produce a biological effect
C.   All of these are correct.
D.   Causal association between a toxin and biological effects
E.   Both causal association between a toxin and biological effects and minimum dosages needed to produce a biological effect
Question #2
Of the following routes of exposure, which one has the most rapid effect?
A.   Inhalation
B.   Intravenous
C.   Ingestion
D.   Intramuscular
E.   Dermal
Question #3
The poisonous substance in Amanita phalloides (“death cap” mushroom) is an example of a(n):
A.   anthropogenic form of poison
B.   poison caused by bacterial activity.
C.   toxicant.
D.   toxin.
E.   None of these is correct.
Question #4
Subacute exposures are those that last for:
A.   1 month or less.
B.   less than 24 hours and occur more than once.
C.   more than 3 months.
D.   less than 24 hours and occur once.
E.   1 to 3 months.
Question #5
One of the founders of toxicology was:
A.   Socrates.
B.   Theophrastus.
C.   Claudius.
D.   Da Vinci.
E.   Paracelsus.
Question #6
The concentration and toxicity of a chemical in the body are affected by:
A.   duration of exposure.
B.   All of these are correct.
C.   route of entry into the body.
D.   individual sensitivity.
E.   received dose of the chemical.
Question #7
An internal dose refers to the:
A.   portion of a substance that becomes internalized in the body.
B.   dose acquired by contact with contaminated environmental sources.
C.   quantity of a substance that is administered
D.   amount of a substance that is available to the internal organs of the body.
E.   None of these is correct.
Question #8
Which of the following is an example of in vitro testing for toxicology?
A.   Experiments with cells derived from human sources
B.   Dose-response assessments in human populations
C.   Studies of animals exposed to toxins
D.   Experiments with normal volunteers
E.   Experiments with volunteers who have had unintentional exposures
Question #9
When highly controlled and standardized conditions are desired, human subjects are used in toxicologic testing.
A.   FALSE
B.   TRUE
Question #10
Which term indicates that the combined effect of exposures to two or more chemicals that is greater than the sum of their individual effects?
A.   Coalitive
B.   Synergistic
C.   Antagonistic
D.   Additive
Question #11
All of the following statements about thalidomide are true, except:
A.   it was developed before the advent of rigorous clinical trials.
B.   it was associated with heart problems among adults.
C.   it was used to treat morning sickness during pregnancy.
D.   it was a potent teratogen.

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