EOH 353 - Global Perspective of Environmental Health » Spring 2020 » Chapter 3 Quiz

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Question #1
The existence of a dose-response relationship may be used to establish which of the following kinds of information?
A.   All of these are correct.
B.   Both causal association between a toxin and biological effects and minimum dosages needed to produce a biological effect
C.   Minimum dosages needed to produce a biological effect
D.   Rate of accumulation of harmful effects
E.   Causal association between a toxin and biological effects
Question #2
Of the following routes of exposure, which one has the most rapid effect?
A.   Dermal
B.   Inhalation
C.   Ingestion
D.   Intravenous
E.   Intramuscular
Question #3
The poisonous substance in Amanita phalloides (“death cap” mushroom) is an example of a(n):
A.   None of these is correct.
B.   poison caused by bacterial activity.
C.   anthropogenic form of poison
D.   toxin.
E.   toxicant.
Question #4
Subacute exposures are those that last for:
A.   1 to 3 months.
B.   less than 24 hours and occur once.
C.   more than 3 months.
D.   less than 24 hours and occur more than once.
E.   1 month or less.
Question #5
One of the founders of toxicology was:
A.   Paracelsus.
B.   Theophrastus.
C.   Da Vinci.
D.   Claudius.
E.   Socrates.
Question #6
The concentration and toxicity of a chemical in the body are affected by:
A.   All of these are correct.
B.   duration of exposure.
C.   individual sensitivity.
D.   received dose of the chemical.
E.   route of entry into the body.
Question #7
An internal dose refers to the:
A.   dose acquired by contact with contaminated environmental sources.
B.   amount of a substance that is available to the internal organs of the body.
C.   None of these is correct.
D.   portion of a substance that becomes internalized in the body.
E.   quantity of a substance that is administered
Question #8
Which of the following is an example of in vitro testing for toxicology?
A.   Experiments with cells derived from human sources
B.   Dose-response assessments in human populations
C.   Experiments with normal volunteers
D.   Studies of animals exposed to toxins
E.   Experiments with volunteers who have had unintentional exposures
Question #9
When highly controlled and standardized conditions are desired, human subjects are used in toxicologic testing.
A.   FALSE
B.   TRUE
Question #10
Which term indicates that the combined effect of exposures to two or more chemicals that is greater than the sum of their individual effects?
A.   Additive
B.   Antagonistic
C.   Synergistic
D.   Coalitive
Question #11
All of the following statements about thalidomide are true, except:
A.   it was associated with heart problems among adults.
B.   it was a potent teratogen.
C.   it was developed before the advent of rigorous clinical trials.
D.   it was used to treat morning sickness during pregnancy.

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